HitPredict

Interactor 1: EXOS9 (Q06265)
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)
Gene: EXOSC9

Interactor 2: RBM7 (Q9Y580)
RNA-binding protein 7 (RNA-binding motif protein 7)
Gene: RBM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 24981860
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 439 Hs			1 266
+	Hs
		1285003 EXOS8_HUMAN (1-275): 1.68e-86: 267: 26.98		RBM7_HUMAN (1-266): 2.96e-58: 188: 100.00
+	Hs
		1063788 EXOS7_HUMAN (1-284): 9.95e-83: 257: 26.12		RBM7_HUMAN (1-266): 2.96e-58: 188: 100.00
+	Sc
		376931 RRP45_YEAST (2-290): 7.5e-80: 250: 33.78		PABP_YEAST (10-258): 4.72e-37: 139: 15.22
+	Hs
		1342634 EXOS4_HUMAN (14-277): 2.36e-51: 175: 14.76		RBM7_HUMAN (1-266): 2.96e-58: 188: 100.00
+	Sc
		376977 RRP42_YEAST (4-267): 2.09e-41: 149: 16.43		PABP_YEAST (10-258): 4.72e-37: 139: 15.22