Protein: PPID
Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (40 kDa peptidyl-prolyl cis-trans isomerase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein) (Rotamase D)

Gene: PPID
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q08752

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

461404

HS90A
Heat shock protein HSP 90-alpha

4

13

Small-scale

0.696

High

944880

PCBP4
Poly(rC)-binding protein 4

3

3

High-throughput

0.667

High

387827

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

1

High-throughput

0.628

High

986369

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

11

High-throughput

0.618

High

1064876

TEBP
Prostaglandin E synthase 3

2

3

Small-scale

0.611

High

725866

FGF9
Fibroblast growth factor 9

2

0

High-throughput

0.602

High

1064879

AKIR2
Akirin-2

2

0

High-throughput

0.602

High

1064893

TMA16
Translation machinery-associated protein 16

2

0

High-throughput

0.602

High

468302

HS90B
Heat shock protein HSP 90-beta

2

13

Small-scale

0.602

High

558072

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.597

High

658134

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.597

High

992706

RACK1
Small ribosomal subunit protein RACK1

1

4

Small-scale

0.597

High

1064870

ILF2
Interleukin enhancer-binding factor 2

1

2

Small-scale

0.597

High

421994

A4
Amyloid-beta precursor protein

2

4

Small-scale

0.595

High

438955

DCUP
Uroporphyrinogen decarboxylase

2

0

High-throughput

0.585

High

537045

HSP7C
Heat shock cognate 71 kDa protein

2

3

Small-scale

0.585

High

404007

GCR
Glucocorticoid receptor

2

8

Small-scale

0.584

High

522082

BCL2
Apoptosis regulator Bcl-2

1

2

Small-scale

0.573

High

1064889

SH2D3
SH2 domain-containing protein 3C

2

6

High-throughput

0.571

High

445170

S10A6
Protein S100-A6

1

5

Small-scale

0.561

High

657032

S10A1
Protein S100-A1

1

4

Small-scale

0.561

High

869853

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

1

Small-scale

0.561

High

928174

HAP1
Huntingtin-associated protein 1

1

3

High-throughput

0.541

High

336221

ZIC2
Zinc finger protein ZIC 2

1

1

High-throughput

0.536

High

336943

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

1

High-throughput

0.536

High

1025216

HXC5
Homeobox protein Hox-C5

1

1

High-throughput

0.536

High

1064874

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.536

High

1064877

CDC37
Hsp90 co-chaperone Cdc37

1

2

High-throughput

0.536

High

1064887

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

4

High-throughput

0.536

High

1064892

AEN
Apoptosis-enhancing nuclease

1

1

High-throughput

0.536

High

1064894

GSX1
GS homeobox 1

1

2

High-throughput

0.536

High

331996

KAT7
Histone acetyltransferase KAT7

1

0

High-throughput

0.518

High

1064875

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

706110

S10A2
Protein S100-A2

1

5

Small-scale

0.512

High

919913

PLK1
Serine/threonine-protein kinase PLK1

1

4

High-throughput

0.508

High

395986

ESR1
Estrogen receptor

1

8

Small-scale

0.501

High

456102

FES
Tyrosine-protein kinase Fes/Fps

1

4

Small-scale

0.501

High

1026338

HSF1
Heat shock factor protein 1

1

1

Small-scale

0.501

High

1064890

LNX1
E3 ubiquitin-protein ligase LNX

1

6

Small-scale

0.501

High

868502

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.493

High

389321

FINC
Fibronectin

1

3

High-throughput

0.489

High

1064886

GPAM1
GPALPP motifs-containing protein 1

1

1

High-throughput

0.489

High

995003

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

571945

TRI27
Zinc finger protein RFP

1

3

High-throughput

0.481

High

1064891

FBX25
F-box only protein 25

1

0

Small-scale

0.480

High

259852

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.479

High

400715

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

413709

P53
Cellular tumor antigen p53

1

3

Small-scale

0.479

High

440047

LCK
Tyrosine-protein kinase Lck

1

2

High-throughput

0.479

High

446946

NPM
Nucleophosmin

1

1

Small-scale

0.479

High

467786

MCR
Mineralocorticoid receptor

1

8

Small-scale

0.479

High

519983

ANDR
Androgen receptor

1

8

Small-scale

0.479

High

529699

TAU
Microtubule-associated protein tau

1

8

Small-scale

0.479

High

703554

MK01
Mitogen-activated protein kinase 1

1

1

Small-scale

0.479

High

862069

YAP1
Transcriptional coactivator YAP1

1

9

High-throughput

0.479

High

891492

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.479

High

996119

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.479

High

1051738

EF1A2
Elongation factor 1-alpha 2

1

3

High-throughput

0.479

High

1064872

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

5

High-throughput

0.479

High

1064873

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

2

High-throughput

0.479

High

1064882

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1064896

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

483903

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.458

High

1064871

REST
RE1-silencing transcription factor

1

0

High-throughput

0.458

High

1064881

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

407850

SEMG1
Semenogelin-1

1

1

High-throughput

0.445

High

457388

TBB5
Tubulin beta chain

1

1

Small-scale

0.445

High

952778

ACTB
Actin, cytoplasmic 1

1

2

Small-scale

0.445

High

996670

TBA1B
Tubulin alpha-1B chain

1

4

Small-scale

0.445

High

997299

TBB4B
Tubulin beta-4B chain

1

1

Small-scale

0.445

High

1036564

SEMG2
Semenogelin-2

1

1

High-throughput

0.445

High

1064883

TBA1A
Tubulin alpha-1A chain

1

4

Small-scale

0.445

High

1064895

DDX28
Probable ATP-dependent RNA helicase DDX28

1

3

High-throughput

0.445

High

411811

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

1064888

FBXL6
F-box/LRR-repeat protein 6

1

3

High-throughput

0.437

High

330141

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.426

High

598730

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

619761

VCAM1
Vascular cell adhesion protein 1

1

3

High-throughput

0.407

High

1064880

AMTN
Amelotin

2

0

High-throughput

0.328

High

1064885

CCD83
Coiled-coil domain-containing protein 83

2

0

High-throughput

0.328

High

906877

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.279

Low

1064884

CCD71
Coiled-coil domain-containing protein 71

1

0

High-throughput

0.279

Low

1064878

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.269

Low

1064897

ADA29
Disintegrin and metalloproteinase domain-containing protein 29

1

0

High-throughput

0.269

Low

1064898

PCDG9
Protocadherin gamma-A9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025