Interactor 1: ATF4 (Q06507)
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (C/EBP-related ATF) (C/ATF) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2)
Gene: ATF4

Interactor 2: TRIB3 (Q8K4K2)
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase)
Gene: TRIB3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 0.60 0.529

The method score is based on:

Property Details
Experiments 12749859
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0019901 - protein kinase binding
GO:0034976 - response to endoplasmic reticulum stress
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 349
Mm

1 354
+ Hs
+ Hs

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Last updated: 15 Jul 2024