HitPredict

Interactor 1: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Interactor 2: MTUS1 (Q9ULD2)
Microtubule-associated tumor suppressor 1 (AT2 receptor-binding protein) (Angiotensin-II type 2 receptor-interacting protein) (Mitochondrial tumor suppressor 1)
Gene: MTUS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27705803
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 1270
+	Hs
		148711 RING1_HUMAN (1-406): 2.01e-114: 342: 100.00		CTRO_HUMAN (446-1039): 1.02e-20: 101: 8.65
+	Hs
		1253531 RING2_HUMAN (8-406): 4.9e-100: 302: 54.25		CIP2A_HUMAN (844-1239): 2.01e-12: 74.1: 20.43
+	Hs
		718062 BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16		MY18A_HUMAN (732-1270): 2.93e-31: 136: 12.43
+	Hs
		717848 BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16		PLEC_HUMAN (447-1270): 1.04e-26: 121: 9.29
+	Hs
		528393 TRIM6_HUMAN (39-392): 1.17e-47: 171: 12.53		MYH6_HUMAN (441-1247): 1.72e-27: 123: 9.91
+	Hs
		551783 COP1_HUMAN (40-326): 3.5e-39: 151: 18.31		DESP_HUMAN (454-1267): 1.63e-29: 130: 8.90
+	Hs
		584968 RO52_HUMAN (33-392): 4.67e-43: 158: 13.14		PLEC_HUMAN (447-1270): 1.04e-26: 121: 9.29
+	Hs
		254450 BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16		ROCK2_HUMAN (939-1257): 1.14e-11: 71.7: 11.64
+	Hs
		551628 BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63		DESP_HUMAN (454-1267): 1.63e-29: 130: 8.90
+	Hs
		522639 TRIM6_HUMAN (39-392): 1.17e-47: 171: 12.53		MYH7_HUMAN (503-1091): 5.24e-18: 92.5: 9.60
+	Hs
		749516 BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63		PLEC_HUMAN (447-1270): 1.04e-26: 121: 9.29
+	Mm
		1321705 RN138_MOUSE (31-190): 1.32e-45: 159: 18.68		PLEC_MOUSE (681-1265): 1.6e-19: 97.9: 12.33
+	Hs
		148473 BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63		CTRO_HUMAN (446-1039): 1.02e-20: 101: 8.65
+	Hs
		584960 RO52_HUMAN (33-392): 4.67e-43: 158: 13.14		DCTN1_HUMAN (945-1226): 9.76e-14: 78.3: 20.72
+	Hs
		1127137 BARD1_HUMAN (4-335): 2.56e-39: 151: 13.35		MTUS2_HUMAN (606-949): 3.99e-12: 73.3: 10.54
+	Hs
		749488 BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63		DCTN1_HUMAN (945-1226): 9.76e-14: 78.3: 20.72
+	Hs
		749701 BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63		CIP2A_HUMAN (844-1239): 2.01e-12: 74.1: 20.43
+	Hs
		724691 BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63		MYH9_HUMAN (980-1268): 1.48e-10: 68.3: 14.88
+	Hs
		749682 BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63		F184A_HUMAN (875-1234): 2.26e-09: 64.1: 17.51