HitPredict

Interactor 1: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	34079125, 35271311, 26496610
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0035577 - azurophil granule membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 602 Hs			1 249
+	Hs
		310612 CKAP4_HUMAN (1-602): 2e-38: 151: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		502880 LAMC1_HUMAN (304-590): 1.27e-11: 70: 12.71		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1255711 RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		310734 RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1189777 MYH14_HUMAN (127-597): 5.01e-26: 116: 13.49		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34