Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1
Interactor 2: OCLN (Q16625)
Occludin
Gene: OCLN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 0.60 | 0.743 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26090670, 23758859, 9792688, 12169098, 34079125, 26272951, 17087658, 18662404 |
| Identification Methods | affinity chromatography technology, fluorescent resonance energy transfer, pull down, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0030054 - cell junction GO:0032991 - protein-containing complex GO:0035633 - maintenance of blood-brain barrier and 3 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
