HitPredict

Interactor 1: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Interactor 2: SYNE2 (Q8WXH0)
Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2)
Gene: SYNE2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 602 Hs			1 6885
+	Hs
		149115 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		SYNE2_HUMAN (1-6885): 0: 1508: 100.00
+	Hs
		990616 CKAP4_HUMAN (1-602): 2e-38: 151: 100.00		CLMN_HUMAN (18-283): 7.62e-50: 198: 47.06
+	Hs
		149428 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		MACF1_HUMAN (279-2502): 1.13e-48: 197: 10.79
+	Hs
		149277 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		SPTN4_HUMAN (24-301): 1.87e-42: 176: 41.28
+	Hs
		148841 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		PLEC_HUMAN (4832-6877): 3.53e-41: 172: 10.20
+	Hs
		724786 MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78		DYST_HUMAN (282-2999): 6.47e-48: 195: 9.98
+	Hs
		724839 MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78		PLEC_HUMAN (4832-6877): 3.53e-41: 172: 10.20
+	Hs
		990505 CKAP4_HUMAN (1-602): 2e-38: 151: 100.00		SYNE3_HUMAN (4445-5053): 1.36e-10: 70.7: 13.84
+	Hs
		149072 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		SYNE1_HUMAN (5226-6861): 2.45e-16: 90.3: 9.43
+	Hs
		1012563 CGNL1_HUMAN (34-599): 7e-24: 109: 12.13		SYNE3_HUMAN (4445-5053): 1.36e-10: 70.7: 13.84
+	Hs
		148142 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		SPTN2_HUMAN (2344-4109): 4.77e-15: 86: 7.96
+	Hs
		148330 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		SPTB1_HUMAN (5680-6858): 6.17e-12: 75.6: 11.32
+	Hs
		148690 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		SPTB2_HUMAN (5680-6855): 8.14e-12: 75.2: 10.24
+	Hs
		148339 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		ACTN1_HUMAN (4678-5164): 1.7e-10: 70.6: 10.92
+	Hs
		148722 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		ACTN3_HUMAN (6427-6732): 2.66e-09: 66.3: 11.08
+	Hs
		164575 MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78		SPTN2_HUMAN (2344-4109): 4.77e-15: 86: 7.96
+	Hs
		110636 MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78		H3BPE1_HUMAN (5892-6861): 3.68e-14: 82.9: 10.89
+	Hs
		724781 MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78		SPTB2_HUMAN (5680-6855): 8.14e-12: 75.2: 10.24
+	Hs
		502846 LAMC1_HUMAN (304-590): 1.27e-11: 70: 12.71		SYNE3_HUMAN (4445-5053): 1.36e-10: 70.7: 13.84
+	Hs
		521484 MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78		ACTN1_HUMAN (4678-5164): 1.7e-10: 70.6: 10.92