HitPredict

Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: KIF2C (Q99661)
Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK)
Gene: KIF2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1748 Hs			1 725
+	Hs
		990843 ZO1_HUMAN (1-1748): 0: 925: 100.00		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		116734 CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66		KIF2A_HUMAN (10-722): 0: 626: 52.04
+	Ce
		619838 LIN2_CAEEL (104-806): 1.27e-90: 319: 12.90		UN104_CAEEL (257-689): 8.84e-141: 452: 29.87
+	Mm
		660012 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		KIF2A_MOUSE (10-722): 0: 629: 52.25
+	Hs
		1066390 PALS1_HUMAN (272-806): 1.75e-82: 288: 15.67		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		1066234 MPP7_HUMAN (310-807): 3.29e-83: 287: 14.96		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		942384 DLG4_HUMAN (1-112): 2.58e-27: 122: 29.92		KI13B_HUMAN (256-671): 1.33e-140: 455: 29.89
+	Mm
		93501 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		E9Q4K7_MOUSE (256-672): 2.82e-140: 454: 30.05
+	Mm
		660025 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		KIF3A_MOUSE (248-721): 4.84e-146: 444: 26.67
+	Hs
		1020223 PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63		KI13B_HUMAN (256-671): 1.33e-140: 455: 29.89
+	Hs
		280044 MPDZ_HUMAN (31-489): 8.85e-18: 92.6: 13.61		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		1021494 DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		1021567 DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54		KI13B_HUMAN (256-671): 1.33e-140: 455: 29.89
+	Hs
		855629 DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54		KIF11_HUMAN (243-722): 3.2e-145: 452: 28.14
+	Mm
		1160656 DLG1_MOUSE (271-512): 2.6e-16: 87.3: 17.26		KIF11_MOUSE (243-723): 3.09e-144: 450: 28.34
+	Hs
		1066824 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38