HitPredict

Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1748 Hs			1 669
+	Hs
		990832 ZO1_HUMAN (1-1748): 0: 925: 100.00		CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88
+	Hs
		990961 ZO1_HUMAN (1-1748): 0: 925: 100.00		MRCKB_HUMAN (197-560): 2.09e-10: 66.2: 13.44
+	Hs
		990845 ZO1_HUMAN (1-1748): 0: 925: 100.00		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		990862 ZO1_HUMAN (1-1748): 0: 925: 100.00		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		148718 ZO1_HUMAN (1-1748): 0: 925: 100.00		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		847099 PALS2_HUMAN (379-806): 1.23e-83: 287: 15.27		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Hs
		942374 DLG4_HUMAN (1-112): 2.58e-27: 122: 29.92		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Mm
		936186 DLG3_MOUSE (21-396): 1.29e-48: 190: 18.65		N4BP3_MOUSE (17-640): 8.09e-32: 132: 27.16
+	Hs
		280066 MPDZ_HUMAN (31-489): 8.85e-18: 92.6: 13.61		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1255127 DLG5_HUMAN (262-508): 3.83e-17: 90.3: 21.43		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Mm
		1143516 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67
+	Mm
		57139 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		LZTS3_MOUSE (1-669): 3.91e-31: 131: 31.62
+	Hs
		149079 INADL_HUMAN (60-583): 5.65e-19: 96.5: 18.77		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		1145855 DLG5_HUMAN (262-508): 3.83e-17: 90.3: 21.43		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		1268108 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		1145968 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		149386 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36