Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: JAM3 (Q9BX67)
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]
Gene: JAM3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 12953056
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0035633 - maintenance of blood-brain barrier
GO:0070160 - tight junction
GO:0098609 - cell-cell adhesion
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1748
Hs

1 310
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024