HitPredict

Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: CING (Q9P2M7)
Cingulin
Gene: CGN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	34079125, 28514442, 11042084, 33961781, 12023291
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0030054 - cell junction GO:0045296 - cadherin binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1748 Hs			1 1203
+	Hs
		990832 ZO1_HUMAN (1-1748): 0: 925: 100.00		CGNL1_HUMAN (287-1021): 4.96e-33: 141: 25.20
+	Hs
		1020232 PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63		CING_HUMAN (1-1203): 7.29e-107: 366: 100.00
+	Hs
		1350447 ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98		CING_HUMAN (1-1203): 7.29e-107: 366: 100.00