HitPredict

Interactor 1: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Interactor 2: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	21620750
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0035591 - signaling adaptor activity GO:0044877 - protein-containing complex binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 671
+	Mm
		1141325 KHDR1_MOUSE (1-443): 0: 514: 94.36		RIPK1_MOUSE (1-671): 0: 575: 69.49
+	Mm
		639447 KHDR1_MOUSE (1-443): 0: 514: 94.36		LYN_MOUSE (22-289): 6.81e-27: 117: 31.30
+	Hs
		433719 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		LYN_HUMAN (23-289): 6.17e-28: 120: 32.13
+	Hs
		411689 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		LCK_HUMAN (23-289): 1.31e-27: 119: 31.87
+	Hs
		782780 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		CSK_HUMAN (10-285): 1.03e-27: 118: 30.74
+	Hs
		789069 SF01_HUMAN (82-301): 6.63e-54: 192: 21.33		ABL2_HUMAN (11-456): 2.1e-112: 366: 23.56
+	Hs
		337484 SF01_HUMAN (82-301): 6.63e-54: 192: 21.33		ABL1_HUMAN (11-472): 1.06e-102: 340: 24.32
+	Hs
		433822 KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62		LYN_HUMAN (23-289): 6.17e-28: 120: 32.13