Protein: SL9A2
Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2)

Gene: SL9A2, SLC9A2
Organism: Homo sapiens
Interactions: 127
UniProt ID: Q9UBY0

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0008104 - intracellular protein localization
GO:0015385 - sodium:proton antiporter activity
GO:0015386 - potassium:proton antiporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225752

CHP2
Calcineurin B homologous protein 2

2

20

Small-scale

0.755

High

1406244

CHP1
Calcineurin B homologous protein 1

2

20

Small-scale

0.755

High

1117519

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

1

High-throughput

0.665

High

362395

ABL1
Tyrosine-protein kinase ABL1

1

1

Small-scale

0.501

High

386495

SPTA1
Spectrin alpha chain, erythrocytic 1

1

1

Small-scale

0.501

High

557506

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

Small-scale

0.501

High

635756

RASA1
Ras GTPase-activating protein 1

1

3

Small-scale

0.501

High

61147

T131L
Transmembrane protein 131-like

1

6

High-throughput

0.445

High

254238

CTND1
Catenin delta-1

1

4

High-throughput

0.445

High

270596

LRP4
Low-density lipoprotein receptor-related protein 4

1

5

High-throughput

0.445

High

336797

BAG4
BAG family molecular chaperone regulator 4

1

8

High-throughput

0.445

High

347974

BAG3
BAG family molecular chaperone regulator 3

1

8

High-throughput

0.445

High

386327

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

3

High-throughput

0.445

High

531169

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

6

High-throughput

0.445

High

564502

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

Small-scale

0.445

High

605834

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

High-throughput

0.445

High

617354

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

4

High-throughput

0.445

High

634681

LMNB1
Lamin-B1

1

3

High-throughput

0.445

High

691513

1433T
14-3-3 protein theta

1

8

High-throughput

0.445

High

730323

1433B
14-3-3 protein beta/alpha

1

8

High-throughput

0.445

High

896326

PEX5
Peroxisomal targeting signal 1 receptor

1

1

High-throughput

0.445

High

904184

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.445

High

966979

1433G
14-3-3 protein gamma

1

8

High-throughput

0.445

High

972095

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.445

High

988001

GRB2
Growth factor receptor-bound protein 2

1

2

High-throughput

0.445

High

990831

1433Z
14-3-3 protein zeta/delta

1

8

High-throughput

0.445

High

991751

DYL1
Dynein light chain 1, cytoplasmic

1

1

High-throughput

0.445

High

1049873

1433F
14-3-3 protein eta

1

8

High-throughput

0.445

High

1063200

GOGA3
Golgin subfamily A member 3

1

1

High-throughput

0.445

High

1091469

ANK3
Ankyrin-3

1

2

High-throughput

0.445

High

1092505

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

1

High-throughput

0.445

High

1191499

GRDN
Girdin

1

1

High-throughput

0.445

High

1228411

SE1L3
Protein sel-1 homolog 3

1

3

High-throughput

0.445

High

1247028

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.445

High

1249990

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

2

High-throughput

0.445

High

1251460

GGYF2
GRB10-interacting GYF protein 2

1

4

High-throughput

0.445

High

1273295

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

1

High-throughput

0.445

High

1335164

LEMD2
LEM domain-containing protein 2

1

2

High-throughput

0.445

High

1371561

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

6

High-throughput

0.445

High

1386230

ASTRA
Protein Aster-A

1

7

High-throughput

0.445

High

1390742

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.445

High

1399271

ANR27
Ankyrin repeat domain-containing protein 27

1

3

High-throughput

0.445

High

1401950

ERBIN
Erbin

1

1

High-throughput

0.445

High

1405312

PKP4
Plakophilin-4

1

5

High-throughput

0.445

High

1407280

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

1

High-throughput

0.445

High

1408350

PKP2
Plakophilin-2

1

4

High-throughput

0.445

High

1411359

LZTS2
Leucine zipper putative tumor suppressor 2

1

4

High-throughput

0.445

High

1430617

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.445

High

1438380

VEZA
Vezatin

1

2

High-throughput

0.445

High

1439577

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

1

High-throughput

0.445

High

1458887

MRCKB
Serine/threonine-protein kinase MRCK beta

1

4

High-throughput

0.445

High

243196

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.437

High

1458885

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

229093

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.426

High

229838

CALU
Calumenin

1

0

High-throughput

0.426

High

317021

MTA2
Metastasis-associated protein MTA2

1

0

High-throughput

0.426

High

718035

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.426

High

861320

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.426

High

1231887

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

0

High-throughput

0.426

High

1245147

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.426

High

1294024

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.426

High

1458881

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.426

High

176373

SYNEM
Synemin

1

1

High-throughput

0.407

High

231776

PEX1
Peroxisomal ATPase PEX1

1

1

High-throughput

0.407

High

298968

DNJB5
DnaJ homolog subfamily B member 5

1

6

High-throughput

0.407

High

344033

HS74L
Heat shock 70 kDa protein 4L

1

11

High-throughput

0.407

High

600451

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

1

8

High-throughput

0.407

High

600520

ZNF3
Zinc finger protein 3

1

7

High-throughput

0.407

High

625685

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.407

High

679275

DNJB1
DnaJ homolog subfamily B member 1

1

6

High-throughput

0.407

High

844281

MTHR
Methylenetetrahydrofolate reductase

1

3

High-throughput

0.407

High

913909

ZN143
Zinc finger protein 143

1

6

High-throughput

0.407

High

946066

ZN121
Zinc finger protein 121

1

4

High-throughput

0.407

High

946212

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.407

High

995329

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.407

High

1010885

TMF1
TATA element modulatory factor

1

2

High-throughput

0.407

High

1042095

LMNB2
Lamin-B2

1

3

High-throughput

0.407

High

1063673

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.407

High

1112272

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.407

High

1135151

CUL7
Cullin-7

1

3

High-throughput

0.407

High

1152058

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

1

High-throughput

0.407

High

1153676

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

6

High-throughput

0.407

High

1161248

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.407

High

1206918

TOIP1
Torsin-1A-interacting protein 1

1

1

High-throughput

0.407

High

1211086

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

3

High-throughput

0.407

High

1217573

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

4

High-throughput

0.407

High

1231955

MRCKG
Serine/threonine-protein kinase MRCK gamma

1

5

High-throughput

0.407

High

1272844

DHX32
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

1

2

High-throughput

0.407

High

1277091

PRIC2
Prickle-like protein 2

1

5

High-throughput

0.407

High

1290793

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.407

High

1307666

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.407

High

1329709

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

1

High-throughput

0.407

High

1330245

ZN655
Zinc finger protein 655

1

4

High-throughput

0.407

High

1335981

B3GL2
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2

1

2

High-throughput

0.407

High

1365256

HS105
Heat shock protein 105 kDa

1

11

High-throughput

0.407

High

1371756

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

6

High-throughput

0.407

High

1382740

JKIP2
Janus kinase and microtubule-interacting protein 2

1

5

High-throughput

0.407

High

1385001

COA7
Cytochrome c oxidase assembly factor 7

1

3

High-throughput

0.407

High

1385176

ATG2B
Autophagy-related protein 2 homolog B

1

3

High-throughput

0.407

High

1395154

DCAF5
DDB1- and CUL4-associated factor 5

1

3

High-throughput

0.407

High

1398320

PRIC1
Prickle-like protein 1

1

5

High-throughput

0.407

High

1454789

FRM4A
FERM domain-containing protein 4A

1

1

High-throughput

0.407

High

1458878

SUN2
SUN domain-containing protein 2

1

2

High-throughput

0.407

High

1458882

PNMA2
Paraneoplastic antigen Ma2

1

3

High-throughput

0.407

High

1458883

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

High-throughput

0.407

High

1458884

TMED3
Transmembrane emp24 domain-containing protein 3

1

2

High-throughput

0.407

High

60774

MEIOC
Meiosis-specific coiled-coil domain-containing protein MEIOC

1

0

High-throughput

0.232

Low

561155

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.232

Low

627728

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

714489

PML
Protein PML

1

0

High-throughput

0.232

Low

991117

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

High-throughput

0.232

Low

1013473

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.232

Low

1066199

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

0

High-throughput

0.232

Low

1085117

KIF1A
Kinesin-like protein KIF1A

1

0

High-throughput

0.232

Low

1277825

PEX26
Peroxisome assembly protein 26

1

0

High-throughput

0.232

Low

1279246

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.232

Low

1288600

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.232

Low

1311120

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.232

Low

1325532

FBXW8
F-box/WD repeat-containing protein 8

1

0

High-throughput

0.232

Low

1329648

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.232

Low

1370763

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

0

High-throughput

0.232

Low

1413083

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.232

Low

1416379

CAR10
Caspase recruitment domain-containing protein 10

1

0

High-throughput

0.232

Low

1439553

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

0

High-throughput

0.232

Low

1458879

DCDC2
Doublecortin domain-containing protein 2

1

0

High-throughput

0.232

Low

1458880

HSPB8
Heat shock protein beta-8

1

0

High-throughput

0.232

Low

1458886

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025