Interactor 1: GDNF (Q07731)
Glial cell line-derived neurotrophic factor (Astrocyte-derived trophic factor) (ATF)
Gene: GDNF

Interactor 2: GFRA1 (Q62997)
GDNF family receptor alpha-1 (GDNF receptor alpha-1) (GDNFR-alpha-1) (GFR-alpha-1) (RET ligand 1) (TGF-beta-related neurotrophic factor receptor 1)
Gene: GFRA1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 9192898, 8674117
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains GDNF~TGF_beta
Common GO terms GO:0005615 - extracellular space
GO:0005794 - Golgi apparatus
GO:0007399 - nervous system development
GO:0008584 - male gonad development
GO:0030182 - neuron differentiation
and 4 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 211
Rn

1 468
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024