Protein: DYLT1
Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog)

Gene: DYLT1, DYNLT1
Organism: Homo sapiens
Interactions: 226
UniProt ID: P63172

Gene Ontology (top 5):
GO:0000132 - establishment of mitotic spindle orientation
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

991836

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

8

14

Small-scale

0.969

High

991893

DYT2B
Dynein light chain Tctex-type protein 2B

6

10

High-throughput

0.946

High

907967

DYLT3
Dynein light chain Tctex-type 3

4

10

High-throughput

0.894

High

156616

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

3

14

Small-scale

0.849

High

991486

DYL1
Dynein light chain 1, cytoplasmic

2

4

High-throughput

0.811

High

991903

DYL2
Dynein light chain 2, cytoplasmic

2

4

High-throughput

0.789

High

991826

DYLT1
Dynein light chain Tctex-type 1

2

10

Small-scale

0.743

High

991967

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

5

2

High-throughput

0.718

High

210551

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

4

2

High-throughput

0.694

High

991846

DYHC1
Cytoplasmic dynein 1 heavy chain 1

4

1

High-throughput

0.694

High

991856

DYLT4
Dynein light chain Tctex-type 4

1

10

High-throughput

0.691

High

991892

DC2I1
Cytoplasmic dynein 2 intermediate chain 1

3

5

High-throughput

0.656

High

991902

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

3

14

High-throughput

0.656

High

991923

AASD1
Alanyl-tRNA editing protein Aarsd1

3

0

High-throughput

0.636

High

991941

DLRB1
Dynein light chain roadblock-type 1

2

3

High-throughput

0.611

High

258833

DNJA2
DnaJ homolog subfamily A member 2

2

1

High-throughput

0.606

High

555660

ACTN1
Alpha-actinin-1

2

2

High-throughput

0.606

High

991951

HSPB7
Heat shock protein beta-7

2

3

High-throughput

0.606

High

991845

DCTN1
Dynactin subunit 1

2

2

High-throughput

0.601

High

991898

ARHG2
Rho guanine nucleotide exchange factor 2

1

2

Small-scale

0.586

High

140220

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

680841

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.580

High

991868

RRAGA
Ras-related GTP-binding protein A

2

0

High-throughput

0.580

High

991885

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.580

High

991910

NOE3
Noelin-3

2

0

High-throughput

0.580

High

991918

PITX2
Pituitary homeobox 2

2

0

High-throughput

0.580

High

991922

PELO
Protein pelota homolog

2

0

High-throughput

0.580

High

991932

CCD68
Coiled-coil domain-containing protein 68

2

0

High-throughput

0.580

High

991950

UXT
Protein UXT

2

0

High-throughput

0.580

High

789091

NUP62
Nuclear pore glycoprotein p62

1

1

Small-scale

0.561

High

890297

NU153
Nuclear pore complex protein Nup153

1

2

Small-scale

0.561

High

991894

CKAP2
Cytoskeleton-associated protein 2

2

0

High-throughput

0.559

High

991854

ARI4B
AT-rich interactive domain-containing protein 4B

2

3

High-throughput

0.553

High

991917

ACOX2
Peroxisomal acyl-coenzyme A oxidase 2

2

1

High-throughput

0.553

High

991933

KLK15
Kallikrein-15

2

1

High-throughput

0.553

High

270920

CLAP2
CLIP-associating protein 2

1

1

High-throughput

0.536

High

474608

VIME
Vimentin

1

2

High-throughput

0.536

High

727757

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.536

High

845280

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

3

High-throughput

0.536

High

990080

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.536

High

991839

CUL3
Cullin-3

1

1

High-throughput

0.536

High

991849

MARE2
Microtubule-associated protein RP/EB family member 2

1

3

High-throughput

0.536

High

991850

MARE1
Microtubule-associated protein RP/EB family member 1

1

3

High-throughput

0.536

High

991870

CLAP1
CLIP-associating protein 1

1

1

High-throughput

0.536

High

991886

DC2L1
Cytoplasmic dynein 2 light intermediate chain 1

1

4

High-throughput

0.536

High

991889

DLRB2
Dynein light chain roadblock-type 2

1

3

High-throughput

0.536

High

991919

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.536

High

580756

PVR
Poliovirus receptor

1

0

Small-scale

0.529

High

451140

NFL
Neurofilament light polypeptide

1

2

High-throughput

0.515

High

971392

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.513

High

991827

TBB4B
Tubulin beta-4B chain

1

0

High-throughput

0.513

High

991877

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

991912

PSKH2
Serine/threonine-protein kinase H2

1

0

High-throughput

0.513

High

915940

NUP98
Nuclear pore complex protein Nup98-Nup96

1

2

Small-scale

0.512

High

336398

SVIL
Supervillin

1

1

Small-scale

0.501

High

347629

BAG3
BAG family molecular chaperone regulator 3

1

1

Small-scale

0.501

High

830529

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

991947

MARK1
Serine/threonine-protein kinase MARK1

1

0

High-throughput

0.493

High

168839

PLD2
Phospholipase D2

1

1

High-throughput

0.489

High

216661

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.489

High

289859

TIPRL
TIP41-like protein

1

1

High-throughput

0.489

High

991909

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

991915

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

238484

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.486

High

991920

HSPB9
Heat shock protein beta-9

1

0

Small-scale

0.484

High

122748

KIF2A
Kinesin-like protein KIF2A

1

1

High-throughput

0.481

High

991887

DDX54
ATP-dependent RNA helicase DDX54

1

1

High-throughput

0.481

High

361214

SODC
Superoxide dismutase [Cu-Zn]

1

0

Small-scale

0.480

High

421890

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

159602

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.479

High

162536

ANM5
Protein arginine N-methyltransferase 5

1

1

High-throughput

0.479

High

271244

CPNE3
Copine-3

1

1

High-throughput

0.479

High

274528

DNJB6
DnaJ homolog subfamily B member 6

1

2

High-throughput

0.479

High

403963

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

456686

ANXA2
Annexin A2

1

1

High-throughput

0.479

High

463052

YES
Tyrosine-protein kinase Yes

1

2

High-throughput

0.479

High

463444

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.479

High

466019

ANXA6
Annexin A6

1

1

High-throughput

0.479

High

475942

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

1

High-throughput

0.479

High

539314

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

2

High-throughput

0.479

High

547127

PYC
Pyruvate carboxylase, mitochondrial

1

3

High-throughput

0.479

High

716017

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

1

High-throughput

0.479

High

774048

ADDA
Alpha-adducin

1

1

High-throughput

0.479

High

951957

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

3

High-throughput

0.479

High

983445

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

4

High-throughput

0.479

High

984062

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.479

High

991830

DYST
Dystonin

1

3

High-throughput

0.479

High

991838

GAB1
GRB2-associated-binding protein 1

1

1

High-throughput

0.479

High

991843

DSG2
Desmoglein-2

1

1

High-throughput

0.479

High

991866

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

1

High-throughput

0.479

High

991869

NUFP2
FMR1-interacting protein NUFIP2

1

1

High-throughput

0.479

High

991873

LUZP1
Leucine zipper protein 1

1

1

High-throughput

0.479

High

991891

CATIN
Splicing factor Cactin

1

4

High-throughput

0.479

High

991906

GWL
Serine/threonine-protein kinase greatwall

1

1

High-throughput

0.479

High

991948

CT2NL
CTTNBP2 N-terminal-like protein

1

2

High-throughput

0.479

High

991957

MTUS1
Microtubule-associated tumor suppressor 1

1

2

High-throughput

0.479

High

991855

NHSL2
NHS-like protein 2

1

2

High-throughput

0.470

High

528231

THIO
Thioredoxin

1

0

High-throughput

0.460

High

900266

FXR2
RNA-binding protein FXR2

1

0

High-throughput

0.460

High

991833

ILF2
Interleukin enhancer-binding factor 2

1

0

High-throughput

0.460

High

991911

RBM14
RNA-binding protein 14

1

0

High-throughput

0.460

High

991935

DHX33
ATP-dependent RNA helicase DHX33

1

0

High-throughput

0.460

High

124038

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.458

High

262056

NBN
Nibrin

1

0

High-throughput

0.458

High

361532

CERU
Ceruloplasmin

1

0

High-throughput

0.458

High

603228

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.458

High

718797

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.458

High

719309

MPIP3
M-phase inducer phosphatase 3

1

0

High-throughput

0.458

High

770140

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

878932

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

905371

HCFC1
Host cell factor 1

1

0

High-throughput

0.458

High

926327

BLM
RecQ-like DNA helicase BLM

1

0

High-throughput

0.458

High

936642

BRPF1
Peregrin

1

0

High-throughput

0.458

High

947151

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

954944

S10AA
Protein S100-A10

1

0

High-throughput

0.458

High

991837

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

0

High-throughput

0.458

High

991841

ASPP2
Apoptosis-stimulating of p53 protein 2

1

0

High-throughput

0.458

High

991844

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

991847

CND2
Condensin complex subunit 2

1

0

High-throughput

0.458

High

991852

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.458

High

991859

RHG21
Rho GTPase-activating protein 21

1

0

High-throughput

0.458

High

991861

CDCA2
Cell division cycle-associated protein 2

1

0

High-throughput

0.458

High

991872

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.458

High

991876

MA7D3
MAP7 domain-containing protein 3

1

0

High-throughput

0.458

High

991878

KLHL7
Kelch-like protein 7

1

0

High-throughput

0.458

High

991880

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

0

High-throughput

0.458

High

991884

KNL1
Outer kinetochore KNL1 complex subunit KNL1

1

0

High-throughput

0.458

High

991895

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

991899

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.458

High

991901

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.458

High

991924

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

991926

TALD3
Protein TALPID3

1

0

High-throughput

0.458

High

991928

NDEL1
Nuclear distribution protein nudE-like 1

1

0

High-throughput

0.458

High

991931

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.458

High

991939

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

0

High-throughput

0.458

High

991945

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.458

High

991946

MS18A
Protein Mis18-alpha

1

0

High-throughput

0.458

High

991949

IBTK
Inhibitor of Bruton tyrosine kinase

1

0

High-throughput

0.458

High

991953

NRBP
Nuclear receptor-binding protein

1

0

High-throughput

0.458

High

991961

SYNRG
Synergin gamma

1

0

High-throughput

0.458

High

991962

NSF1C
NSFL1 cofactor p47

1

0

High-throughput

0.458

High

174741

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

4

High-throughput

0.437

High

425795

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

3

High-throughput

0.437

High

425898

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.437

High

774277

BASI
Basigin

1

1

High-throughput

0.437

High

928614

PMS1
PMS1 protein homolog 1

1

1

High-throughput

0.437

High

970288

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

991831

KMT2A
Histone-lysine N-methyltransferase 2A

1

2

High-throughput

0.437

High

991835

ACACA
Acetyl-CoA carboxylase 1

1

3

High-throughput

0.437

High

991840

CUL4B
Cullin-4B

1

1

High-throughput

0.437

High

991848

PLEC
Plectin

1

3

High-throughput

0.437

High

991853

AAK1
AP2-associated protein kinase 1

1

2

High-throughput

0.437

High

991865

NFRKB
Nuclear factor related to kappa-B-binding protein

1

1

High-throughput

0.437

High

991867

RFIP1
Rab11 family-interacting protein 1

1

1

High-throughput

0.437

High

991874

CPNE8
Copine-8

1

1

High-throughput

0.437

High

991879

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

2

High-throughput

0.437

High

991890

NOC3L
Nucleolar complex protein 3 homolog

1

1

High-throughput

0.437

High

991896

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

991905

DDX27
Probable ATP-dependent RNA helicase DDX27

1

1

High-throughput

0.437

High

991914

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

3

High-throughput

0.437

High

991916

MINT
Msx2-interacting protein

1

1

High-throughput

0.437

High

991938

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

1

High-throughput

0.437

High

991942

BRWD1
Bromodomain and WD repeat-containing protein 1

1

3

High-throughput

0.437

High

991944

ARGL1
Arginine and glutamate-rich protein 1

1

2

High-throughput

0.437

High

991952

ADDG
Gamma-adducin

1

1

High-throughput

0.437

High

991960

CIZ1
Cip1-interacting zinc finger protein

1

1

High-throughput

0.437

High

880126

PTH2R
Parathyroid hormone 2 receptor

2

0

High-throughput

0.316

High

991882

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

0

High-throughput

0.316

High

991907

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

991871

EMSY
BRCA2-interacting transcriptional repressor EMSY

2

0

High-throughput

0.305

High

991936

WDCP
WD repeat and coiled-coil-containing protein

2

0

High-throughput

0.305

High

991900

HAVR1
Hepatitis A virus cellular receptor 1

1

0

Small-scale

0.292

High

720985

CLIP1
CAP-Gly domain-containing linker protein 1

1

0

High-throughput

0.279

Low

640843

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

Small-scale

0.275

Low

301395

WFS1
Wolframin

1

0

High-throughput

0.268

Low

991842

BMPR2
Bone morphogenetic protein receptor type-2

1

0

Small-scale

0.261

Low

991828

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

0

High-throughput

0.251

Low

991929

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.251

Low

185595

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.249

Low

213104

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.249

Low

246520

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.249

Low

338100

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.249

Low

355634

MOC2A
Molybdopterin synthase sulfur carrier subunit

1

0

High-throughput

0.249

Low

475557

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.249

Low

568396

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

596037

H12
Histone H1.2

1

0

High-throughput

0.249

Low

774997

FUS
RNA-binding protein FUS

1

0

High-throughput

0.249

Low

793686

ETFB
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.249

Low

867024

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.249

Low

920622

ARFP1
Arfaptin-1

1

0

High-throughput

0.249

Low

991829

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.249

Low

991832

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.249

Low

991834

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.249

Low

991851

ELF2
ETS-related transcription factor Elf-2

1

0

High-throughput

0.249

Low

991857

AMER1
APC membrane recruitment protein 1

1

0

High-throughput

0.249

Low

991858

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.249

Low

991860

ZN318
Zinc finger protein 318

1

0

High-throughput

0.249

Low

991862

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

0

High-throughput

0.249

Low

991863

LIN54
Protein lin-54 homolog

1

0

High-throughput

0.249

Low

991864

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

991875

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

991881

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.249

Low

991883

KRI1
Protein KRI1 homolog

1

0

High-throughput

0.249

Low

991888

RPGF6
Rap guanine nucleotide exchange factor 6

1

0

High-throughput

0.249

Low

991897

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.249

Low

991904

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.249

Low

991908

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.249

Low

991913

PHF12
PHD finger protein 12

1

0

High-throughput

0.249

Low

991921

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

991925

GNL3
Guanine nucleotide-binding protein-like 3

1

0

High-throughput

0.249

Low

991927

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

991930

SP130
Histone deacetylase complex subunit SAP130

1

0

High-throughput

0.249

Low

991934

CPVL
Probable serine carboxypeptidase CPVL

1

0

High-throughput

0.249

Low

991937

PKHA5
Pleckstrin homology domain-containing family A member 5

1

0

High-throughput

0.249

Low

991940

ZCC17
Zinc finger CCHC domain-containing protein 17

1

0

High-throughput

0.249

Low

991943

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.249

Low

991954

DDX41
Probable ATP-dependent RNA helicase DDX41

1

0

High-throughput

0.249

Low

991955

TASOR
Protein TASOR

1

0

High-throughput

0.249

Low

991956

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low

991958

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.249

Low

991959

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

991963

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.249

Low

991964

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.249

Low

991965

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

0

High-throughput

0.249

Low

991966

KLF12
Krueppel-like factor 12

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025