HitPredict

Interactor 1: BAX (Q07812)
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)
Gene: BAX

Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 9111042, 21199865, 26496610, 29749471, 28760928, 12853473, 9027312, 19427863, 26186194, 28202514, 28514442, 25115399, 9824152, 12137781, 27684187, 32064756, 33961781, 21852238, 24814347, 14766748 and 12 others

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Identification Methods pull down, x-ray crystallography, affinity chromatography technology, two hybrid, proximity labelling technology, fluorescent resonance energy transfer, unspecified method, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, fluorescence polarization spectroscopy and 1 others

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Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2, BH4~Bcl-2
Common GO terms GO:0001541 - ovarian follicle development
GO:0001836 - release of cytochrome c from mitochondria
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
and 14 others

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Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 192
Hs

1 233
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024