Interactor 1: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1
Interactor 2: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19049976, 22498477, 9765397, 33961781, 18628207, 18641390, 19180116, 19713971, 20577262, 24141421, 33931087, 35123989, 22219388, 17659302, 24443581, 17446862 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy, nuclear magnetic resonance, isothermal titration calorimetry |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BH3~Bcl-2 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0032465 - regulation of cytokinesis and 2 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
