HitPredict

Interactor 1: KLC1 (Q07866)
Kinesin light chain 1 (KLC 1)
Gene: KLC1

Interactor 2: SYNE4 (Q8N205)
Nesprin-4 (KASH domain-containing protein 4) (KASH4) (Nuclear envelope spectrin repeat protein 4)
Gene: SYNE4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 573 Hs			1 404
+	Hs
		1231167 KLC4_HUMAN (5-571): 4.27e-99: 315: 68.53		SYNE4_HUMAN (1-404): 0: 704: 100.00
+	Hs
		1231158 KLC2_HUMAN (5-571): 7.66e-95: 304: 68.43		SYNE4_HUMAN (1-404): 0: 704: 100.00
+	Mm
		1208612 KLC4_MOUSE (5-571): 1.9e-94: 303: 68.01		SYNE4_MOUSE (1-404): 0: 618: 65.35
+	Mm
		291545 KLC2_MOUSE (5-571): 4.03e-89: 288: 68.43		SYNE4_MOUSE (1-404): 0: 618: 65.35
+	Hs
		1173493 TMTC3_HUMAN (184-572): 1.42e-31: 132: 12.76		SYNE4_HUMAN (1-404): 0: 704: 100.00
+	Hs
		1159981 KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65		SYNE4_HUMAN (1-404): 0: 704: 100.00
+	Mm
		291540 KLC1_MOUSE (336-567): 6.23e-19: 92.4: 21.16		SYNE4_MOUSE (1-404): 0: 618: 65.35
+	Mm
		1208611 KLC3_MOUSE (356-571): 1.05e-13: 75.8: 17.41		SYNE4_MOUSE (1-404): 0: 618: 65.35