Interactor 1: SOS1 (Q07889)
Son of sevenless homolog 1 (SOS-1)
Gene: SOS1

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 20936779
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~SH3_1, RhoGEF~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1333
Hs

1 2472
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024