HitPredict

Interactor 1: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Interactor 2: ANS1B (Q7Z6G8)
Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1)
Gene: ANKS1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	20205790
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 4544 Hs			1 1248
+	Hs
		310049 LRP1_HUMAN (24-4544): 0: 3520: 100.00		TNKS1_HUMAN (2-633): 4.94e-56: 215: 14.27
+	Hs
		992707 LRP1_HUMAN (24-4544): 0: 3520: 100.00		TNKS2_HUMAN (2-200): 9.92e-45: 179: 23.71
+	Hs
		957621 LRP2_HUMAN (4062-4370): 5.25e-10: 68.7: 11.50		ANS1B_HUMAN (1-1248): 0: 869: 100.00
+	Hs
		474812 NID2_HUMAN (1679-1844): 5.93e-11: 71.4: 24.86		POTEI_HUMAN (24-820): 5.96e-100: 345: 16.76
+	Dm
		422847 NOTCH_DROME (2434-2789): 1.13e-10: 70.6: 11.72		Q9VCM6_DROME (1-949): 3.82e-65: 244: 20.59
+	Hs
		166914 NOTC2_HUMAN (2441-2811): 3.71e-13: 79.1: 10.70		ANR28_HUMAN (151-506): 3.18e-28: 125: 14.25
+	Hs
		980449 NOTC2_HUMAN (2441-2811): 3.71e-13: 79.1: 10.70		ANR44_HUMAN (162-465): 3.61e-27: 121: 12.86
+	Dm
		65546 NOTCH_DROME (2434-2789): 1.13e-10: 70.6: 11.72		A8JNM5_DROME (135-463): 6.09e-24: 112: 17.51
+	Hs
		270281 LRP6_HUMAN (26-203): 6.89e-11: 71.4: 20.44		RIPK4_HUMAN (41-268): 6.23e-13: 75.5: 29.13