Protein: ACTB
Actin, cytoplasmic 1 (Beta-actin) (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]

Gene: ACTB
Organism: Mus musculus
Interactions: 93
UniProt ID: P60710

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0001738 - morphogenesis of a polarized epithelium
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

953290

PROF2
Profilin-2

3

16

Small-scale

0.834

High

953228

PROF1
Profilin-1

3

16

Small-scale

0.829

High

953236

CXAR
Coxsackievirus and adenovirus receptor homolog

1

3

Small-scale

0.761

High

953280

MYH9
Myosin-9

2

14

Small-scale

0.754

High

953245

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

10

Small-scale

0.712

High

953278

AHI1
Jouberin

1

12

High-throughput

0.691

High

953286

COTL1
Coactosin-like protein

1

14

Small-scale

0.680

High

591027

KPCE
Protein kinase C epsilon type

1

6

Small-scale

0.665

High

616470

COF1
Cofilin-1

1

20

Small-scale

0.618

High

953231

RACK1
Small ribosomal subunit protein RACK1

1

9

Small-scale

0.618

High

953237

RN5A
2-5A-dependent ribonuclease

1

8

Small-scale

0.618

High

953255

TPM4
Tropomyosin alpha-4 chain

1

16

Small-scale

0.618

High

953263

FLNB
Filamin-B

1

20

Small-scale

0.618

High

953281

EED
Polycomb protein EED

1

13

High-throughput

0.618

High

953284

PLST
Plastin-3

1

20

Small-scale

0.618

High

701367

MT3
Metallothionein-3

2

1

Small-scale

0.584

High

953257

NEB2
Neurabin-2

2

13

High-throughput

0.584

High

267263

CSKP
Peripheral plasma membrane protein CASK

1

4

Small-scale

0.575

High

616105

KS6A1
Ribosomal protein S6 kinase alpha-1

1

9

Small-scale

0.575

High

953241

MILK2
MICAL-like protein 2

1

15

Small-scale

0.575

High

953256

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

3

Small-scale

0.575

High

953283

CDK9
Cyclin-dependent kinase 9

1

15

Small-scale

0.575

High

953289

DMAP1
DNA methyltransferase 1-associated protein 1

1

5

High-throughput

0.575

High

953274

KAT5
Histone acetyltransferase KAT5

2

11

Small-scale

0.571

High

953282

TRPM7
Transient receptor potential cation channel subfamily M member 7

2

4

Small-scale

0.571

High

97578

E9PV60
WD repeat and FYVE domain containing 4

1

10

High-throughput

0.553

High

953291

SRCN1
SRC kinase signaling inhibitor 1

1

0

High-throughput

0.546

High

953238

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

8

High-throughput

0.536

High

953247

MKS1
Tectonic-like complex member MKS1

1

1

High-throughput

0.536

High

953260

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

5

High-throughput

0.536

High

953264

MYOME
Myomegalin

1

14

High-throughput

0.536

High

953268

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

2

High-throughput

0.536

High

953292

NPHP1
Nephrocystin-1

1

1

High-throughput

0.536

High

59594

A2AM57
Inversin

1

7

High-throughput

0.489

High

771447

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

5

High-throughput

0.484

High

953230

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.481

High

97380

PRRT2
Proline-rich transmembrane protein 2

1

2

High-throughput

0.479

High

98320

E9QKZ2
Importin 9

1

1

Small-scale

0.479

High

108562

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

236972

PROM1
Prominin-1

1

1

Small-scale

0.479

High

267133

PKNX1
Homeobox protein PKNOX1

1

1

Small-scale

0.479

High

312356

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

14

Small-scale

0.479

High

542836

RARA
Retinoic acid receptor alpha

1

13

Small-scale

0.479

High

895998

VATA
V-type proton ATPase catalytic subunit A

1

2

Small-scale

0.479

High

944125

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

4

Small-scale

0.479

High

947651

NPHP4
Nephrocystin-4

1

3

High-throughput

0.479

High

949800

PCBP1
Poly(rC)-binding protein 1

1

8

Small-scale

0.479

High

953227

YBOX1
Y-box-binding protein 1

1

2

Small-scale

0.479

High

953232

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

953233

ELAV1
ELAV-like protein 1

1

4

Small-scale

0.479

High

953234

DAB1
Disabled homolog 1

1

3

Small-scale

0.479

High

953242

FUBP2
Far upstream element-binding protein 2

1

14

Small-scale

0.479

High

953243

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

4

High-throughput

0.479

High

953246

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

15

Small-scale

0.479

High

953248

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

2

Small-scale

0.479

High

953249

ELAV4
ELAV-like protein 4

1

4

Small-scale

0.479

High

953250

PCBP2
Poly(rC)-binding protein 2

1

12

Small-scale

0.479

High

953251

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

2

Small-scale

0.479

High

953252

INADL
InaD-like protein

1

5

Small-scale

0.479

High

953253

TFE3
Transcription factor E3

1

5

High-throughput

0.479

High

953254

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.479

High

953258

SPOP
Speckle-type POZ protein

1

12

High-throughput

0.479

High

953259

TRPV1
Transient receptor potential cation channel subfamily V member 1

1

2

High-throughput

0.479

High

953261

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

2

Small-scale

0.479

High

953262

FACD2
Fanconi anemia group D2 protein homolog

1

8

High-throughput

0.479

High

953265

DMRT2
Doublesex- and mab-3-related transcription factor 2

1

1

Small-scale

0.479

High

953269

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

1

High-throughput

0.479

High

953270

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

3

Small-scale

0.479

High

953276

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

16

Small-scale

0.479

High

953279

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.479

High

953285

FBX32
F-box only protein 32

1

6

High-throughput

0.479

High

953287

RING2
E3 ubiquitin-protein ligase RING2

1

20

Small-scale

0.479

High

953288

SET
Protein SET

1

3

Small-scale

0.479

High

953293

PRKN
E3 ubiquitin-protein ligase parkin

1

15

Small-scale

0.479

High

953294

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

16

Small-scale

0.479

High

953295

ILF3
Interleukin enhancer-binding factor 3

1

19

Small-scale

0.479

High

953239

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

953266

PDIP3
Polymerase delta-interacting protein 3

1

0

Small-scale

0.458

High

953277

MATR3
Matrin-3

1

0

Small-scale

0.458

High

953272

PKHH2
Pleckstrin homology domain-containing family H member 2

1

4

Small-scale

0.457

High

204790

ST2B1
Sulfotransferase 2B1

1

1

Small-scale

0.445

High

450388

CSF1
Macrophage colony-stimulating factor 1

1

1

Small-scale

0.445

High

555571

NR4A1
Nuclear receptor subfamily 4 group A member 1

1

14

Small-scale

0.445

High

953229

TCTP
Translationally-controlled tumor protein

1

2

Small-scale

0.445

High

953244

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.445

High

953273

FTM
Protein fantom

1

18

High-throughput

0.445

High

398217

CFAD
Complement factor D

1

4

High-throughput

0.437

High

694295

LIPC
Hepatic triacylglycerol lipase

1

2

Small-scale

0.437

High

953240

Q3TIX6
Far upstream element

1

14

Small-scale

0.437

High

953267

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

6

High-throughput

0.437

High

953275

TTC23
Tetratricopeptide repeat protein 23

1

1

High-throughput

0.437

High

953271

RD3
Protein RD3

1

0

Small-scale

0.426

High

953235

THIOM
Thioredoxin, mitochondrial

1

8

High-throughput

0.407

High


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Last updated: 11Aug2025