HitPredict

Interactor 1: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Interactor 2: GULP1 (Q9UBP9)
PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP)
Gene: GULP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	11729193
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4544 Hs			1 304
+	Hs
		992700 LRP1_HUMAN (24-4544): 0: 3520: 100.00		APBA2_HUMAN (16-296): 5.35e-63: 213: 19.02
+	Hs
		666087 LRP1_HUMAN (24-4544): 0: 3520: 100.00		SHC1_HUMAN (4-286): 1.95e-62: 208: 16.72
+	Mm
		956233 LRP1_MOUSE (24-4544): 0: 3516: 98.08		DAB1_MOUSE (19-259): 2.59e-62: 208: 21.84
+	Hs
		269141 LRP1_HUMAN (24-4544): 0: 3520: 100.00		DAB1_HUMAN (19-259): 2.44e-60: 203: 21.84
+	Hs
		957171 LRP1_HUMAN (24-4544): 0: 3520: 100.00		DAB2_HUMAN (19-283): 1.56e-52: 185: 18.09
+	Hs
		992682 LRP1_HUMAN (24-4544): 0: 3520: 100.00		ANS1B_HUMAN (2-211): 6e-52: 185: 26.42
+	Hs
		992729 LRP1_HUMAN (24-4544): 0: 3520: 100.00		JIP1_HUMAN (27-154): 2.45e-34: 133: 32.59
+	Mm
		1265300 LRP1_MOUSE (24-4544): 0: 3516: 98.08		JIP1_MOUSE (27-154): 1.19e-34: 134: 33.33
+	Hs
		120900 LRP1_HUMAN (24-4544): 0: 3520: 100.00		APBB1_HUMAN (27-162): 3.49e-11: 65.7: 20.59
+	Mm
		956222 VLDLR_MOUSE (27-282): 6.31e-12: 74.5: 17.42		DAB1_MOUSE (19-259): 2.59e-62: 208: 21.84
+	Mm
		729617 LDLR_MOUSE (4194-4517): 3.61e-11: 71.8: 10.69		DAB1_MOUSE (19-259): 2.59e-62: 208: 21.84
+	Mm
		966336 NOTC1_MOUSE (3253-3657): 4.09e-10: 69.1: 11.79		NUMB_MOUSE (1-298): 5e-62: 209: 19.88
+	Hs
		269133 VLDLR_HUMAN (27-282): 1.03e-11: 73.7: 18.49		DAB1_HUMAN (19-259): 2.44e-60: 203: 21.84
+	Hs
		269134 LRP2_HUMAN (4062-4370): 5.25e-10: 68.7: 11.50		DAB1_HUMAN (19-259): 2.44e-60: 203: 21.84
+	Dm
		422717 NOTCH_DROME (2434-2789): 1.13e-10: 70.6: 11.72		NUMB_DROME (2-276): 2.41e-54: 187: 18.93
+	Hs
		270287 LRP6_HUMAN (26-203): 6.89e-11: 71.4: 20.44		DAB2_HUMAN (19-283): 1.56e-52: 185: 18.09
+	Rn
		88518 LRP2_RAT (4250-4538): 2.9e-10: 69.5: 14.33		ARH_RAT (7-252): 3.07e-51: 172: 22.18
+	Dm
		422847 NOTCH_DROME (2434-2789): 1.13e-10: 70.6: 11.72		Q9VCM6_DROME (5-156): 2.79e-46: 168: 31.17
+	Rn
		292326 LRP2_RAT (4250-4538): 2.9e-10: 69.5: 14.33		DAB2_RAT (19-149): 2.19e-38: 145: 27.48
+	Mm
		1337450 LRP1B_MOUSE (2-282): 3.55e-13: 79.1: 18.58		JIP1_MOUSE (27-154): 1.19e-34: 134: 33.33