HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: LARP4 (Q71RC2)
La-related protein 4 (La ribonucleoprotein domain family member 4)
Gene: LARP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 724
+	Hs
		516568 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		LARP4_HUMAN (1-724): 9.66e-130: 403: 100.00
+	Hs
		992864 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Hs
		403210 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		LA_HUMAN (119-325): 8.13e-45: 167: 15.66
+	Hs
		403211 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		LA_HUMAN (119-325): 8.13e-45: 167: 15.66
+	Hs
		1028690 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40
+	Hs
		1028954 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40
+	Hs
		1028680 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		1028941 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		1028701 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		993738 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40
+	Hs
		1028964 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		992809 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40
+	Hs
		993731 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		992797 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		993744 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Mm
		985651 SRSF1_MOUSE (1-235): 1.04e-49: 165: 100.00		LARP7_MOUSE (123-413): 4.14e-32: 133: 13.68
+	Hs
		992815 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		516553 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40
+	Hs
		516541 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		516561 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72