HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 2896
+	Hs
		516766 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		PRC2C_HUMAN (1-2896): 0: 771: 100.00
+	Hs
		1029050 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		MINT_HUMAN (22-1891): 2.31e-43: 178: 9.12
+	Hs
		992912 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		DIDO1_HUMAN (88-631): 5.4e-37: 156: 16.09
+	Hs
		1028876 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Dm
		644444 SRR55_DROME (17-183): 2.57e-52: 175: 39.79		Q9VLS7_DROME (1208-2548): 1.93e-23: 111: 9.16
+	Hs
		1029163 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		993872 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		992995 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		1029046 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		1084386 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		DIDO1_HUMAN (88-631): 5.4e-37: 156: 16.09
+	Hs
		993735 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		PRC2B_HUMAN (894-2896): 3.68e-13: 78.3: 6.73
+	Hs
		516406 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		516609 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		TITIN_HUMAN (1221-2896): 4.19e-20: 101: 7.44
+	Hs
		516749 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		516595 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		KMT2C_HUMAN (1901-2885): 8.54e-14: 80.6: 9.27
+	Hs
		516546 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		PRC2B_HUMAN (894-2896): 3.68e-13: 78.3: 6.73
+	Hs
		952179 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		1084451 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		820908 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		952089 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73