HitPredict

Interactor 1: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk

Interactor 2: Q5U0V7 (Q5U0V7)
phosphoinositide 5-phosphatase (EC 3.1.3.36)
Gene: Synj

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22028469
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 1218
+	Hs
		166042 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		SYNJ2_HUMAN (1-1212): 0: 1030: 39.09
+	Hs
		166023 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		SYNJ2_HUMAN (1-1212): 0: 1030: 39.09
+	Hs
		166030 NCK1_HUMAN (5-143): 2.4e-20: 89.4: 32.35		SYNJ2_HUMAN (1-1212): 0: 1030: 39.09
+	Hs
		166056 ITSN2_HUMAN (72-211): 1.54e-13: 70.8: 19.01		SYNJ2_HUMAN (1-1212): 0: 1030: 39.09
+	Hs
		166055 SH3K1_HUMAN (3-60): 1.52e-13: 70.4: 27.12		SYNJ2_HUMAN (1-1212): 0: 1030: 39.09
+	Hs
		166024 FYN_HUMAN (160-211): 2.56e-12: 66.9: 27.78		SYNJ2_HUMAN (1-1212): 0: 1030: 39.09
+	Hs
		166049 ITSN1_HUMAN (44-209): 1.56e-11: 65: 11.48		SYNJ2_HUMAN (1-1212): 0: 1030: 39.09
+	Ce
		105280 Q95PW9_CAEEL (4-147): 4.6e-19: 85.9: 33.14		SYNJ_CAEEL (5-1085): 0: 906: 39.23
+	Mm
		1141165 GRB2_MOUSE (1-210): 7.86e-65: 201: 63.08		SHIP1_MOUSE (491-1209): 8.05e-151: 486: 20.99
+	Hs
		924485 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		OCRL_HUMAN (502-901): 5.07e-133: 430: 31.37
+	Hs
		924742 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		SHIP1_HUMAN (408-1218): 1.02e-114: 388: 19.57
+	Mm
		337638 ABL1_MOUSE (4-138): 3.18e-23: 98.6: 36.43		SHIP1_MOUSE (491-1209): 8.05e-151: 486: 20.99
+	Hs
		412137 FYN_HUMAN (160-211): 2.56e-12: 66.9: 27.78		OCRL_HUMAN (502-901): 5.07e-133: 430: 31.37
+	Hs
		557759 NCK1_HUMAN (5-143): 2.4e-20: 89.4: 32.35		SHIP1_HUMAN (408-1218): 1.02e-114: 388: 19.57
+	Hs
		802685 CRK_HUMAN (48-209): 9e-20: 87: 29.69		SHIP1_HUMAN (408-1218): 1.02e-114: 388: 19.57
+	Hs
		1271562 SH3K1_HUMAN (3-60): 1.52e-13: 70.4: 27.12		SHIP1_HUMAN (408-1218): 1.02e-114: 388: 19.57
+	Hs
		203218 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		SYNJ1_HUMAN (808-1143): 1.98e-09: 64.4: 12.89
+	Hs
		203208 NCK1_HUMAN (5-143): 2.4e-20: 89.4: 32.35		SYNJ1_HUMAN (808-1143): 1.98e-09: 64.4: 12.89
+	Hs
		203241 SH3K1_HUMAN (3-60): 1.52e-13: 70.4: 27.12		SYNJ1_HUMAN (808-1143): 1.98e-09: 64.4: 12.89
+	Hs
		203228 ITSN1_HUMAN (44-209): 1.56e-11: 65: 11.48		SYNJ1_HUMAN (808-1143): 1.98e-09: 64.4: 12.89