Protein: MTFR2
Mitochondrial fission regulator 2 (DUF729 domain-containing protein 1)

Gene: MTFR2
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q6P444

Gene Ontology (top 5):
GO:0000266 - mitochondrial fission
GO:0005739 - mitochondrion
GO:0007005 - mitochondrion organization
GO:0009060 - aerobic respiration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1242121

S2546
Mitochondrial outer membrane protein SLC25A46

2

2

Small-scale

0.584

High

1242119

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

2

High-throughput

0.574

High

1242131

MTCH1
Mitochondrial carrier homolog 1

2

5

High-throughput

0.571

High

1242138

MTCH2
Mitochondrial carrier homolog 2

2

5

High-throughput

0.571

High

560879

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

0

High-throughput

0.549

High

848964

MAGAC
Melanoma-associated antigen 12

1

2

High-throughput

0.523

High

1063350

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.523

High

1242122

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

High-throughput

0.493

High

775434

DDIT3
DNA damage-inducible transcript 3 protein

1

1

High-throughput

0.489

High

879796

NPY2R
Neuropeptide Y receptor type 2

1

1

High-throughput

0.489

High

993218

ACTG
Actin, cytoplasmic 2

1

2

High-throughput

0.489

High

1113424

CUL3
Cullin-3

1

1

High-throughput

0.489

High

1230094

K1C40
Keratin, type I cytoskeletal 40

1

2

High-throughput

0.489

High

1242117

BAKOR
Beclin 1-associated autophagy-related key regulator

1

1

High-throughput

0.489

High

1242134

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

1

High-throughput

0.489

High

216719

HTRA2
Serine protease HTRA2, mitochondrial

1

2

High-throughput

0.479

High

348568

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.479

High

1125490

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.479

High

1147618

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

1

High-throughput

0.479

High

1242118

MIRO2
Mitochondrial Rho GTPase 2

1

3

High-throughput

0.479

High

1242120

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

1242123

RMD3
Regulator of microtubule dynamics protein 3

1

2

High-throughput

0.479

High

1242124

PHB2
Prohibitin-2

1

2

High-throughput

0.479

High

1242125

DBLOH
Diablo IAP-binding mitochondrial protein

1

1

High-throughput

0.479

High

1242127

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.479

High

1242128

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

1242129

OCAD1
OCIA domain-containing protein 1

1

2

High-throughput

0.479

High

1242130

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

1

High-throughput

0.479

High

1242137

FIS1
Mitochondrial fission 1 protein

1

2

High-throughput

0.479

High

166934

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.458

High

1242126

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.437

High

1242135

DICER
Endoribonuclease Dicer

1

1

High-throughput

0.437

High

1226889

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.407

High

450310

TY3H
Tyrosine 3-monooxygenase

2

0

High-throughput

0.328

High

902351

SCNND
Epithelial sodium channel subunit delta

2

0

High-throughput

0.328

High

1034960

GCYB1
Guanylate cyclase soluble subunit beta-1

2

0

High-throughput

0.328

High

1242132

TMOD4
Tropomodulin-4

2

0

High-throughput

0.328

High

1242136

KLDC2
Kelch domain-containing protein 2

2

0

High-throughput

0.313

High

783303

TRI23
E3 ubiquitin-protein ligase TRIM23

1

0

High-throughput

0.299

High

1242133

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.299

High

563925

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.282

High

880156

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.279

Low

1211256

SNPC4
snRNA-activating protein complex subunit 4

1

0

High-throughput

0.279

Low

540255

SPTB1
Spectrin beta chain, erythrocytic

1

0

High-throughput

0.269

Low

1155469

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

538772

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025