HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: K1H1 (Q15323)
Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)
Gene: KRT31

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.578

Property	Details
Experiments	25416956, 36949045
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 197 Hs			1 416
+	Hs
		993469 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69
+	Hs
		580018 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		K1C15_HUMAN (55-367): 1.79e-111: 336: 57.96
+	Hs
		531465 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		K1C13_HUMAN (50-373): 2.09e-108: 328: 56.00
+	Hs
		49561 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		A1A4E9_HUMAN (50-373): 1.97e-107: 326: 55.39
+	Hs
		993526 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		KRT35_HUMAN (2-411): 6.51e-83: 263: 71.46
+	Hs
		280568 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		KRT34_HUMAN (1-390): 5.34e-79: 251: 89.23