HitPredict

Interactor 1: MSH6 (Q03834)
DNA mismatch repair protein MSH6 (MutS protein homolog 6) (Postmeiotic segregation protein 3)
Gene: MSH6

Interactor 2: CMR1 (Q12510)
DNA damage-binding protein CMR1 (Changed mutation rate protein 1)
Gene: CMR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	11805826, 22199229, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1242 Sc			1 522
+	Hs
		855555 MSH6_HUMAN (60-1198): 0: 1045: 28.78		WDR76_HUMAN (4-515): 2.47e-92: 296: 22.98
+	Hs
		594215 MSH3_HUMAN (164-1176): 0: 884: 23.37		WDR76_HUMAN (4-515): 2.47e-92: 296: 22.98
+	Hs
		794315 MSH2_HUMAN (298-1193): 0: 838: 22.07		WDR76_HUMAN (4-515): 2.47e-92: 296: 22.98
+	Sc
		639299 MSH2_YEAST (314-1209): 0: 713: 20.59		CMR1_YEAST (1-522): 7.95e-112: 343: 100.00
+	Sc
		629357 MSH3_YEAST (310-1210): 0: 668: 22.79		CMR1_YEAST (1-522): 7.95e-112: 343: 100.00