HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32068487
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 835
+	Hs
		992753 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1028638 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		963511 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		993729 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		LIN41_HUMAN (142-395): 1.53e-66: 240: 24.19
+	Hs
		1029067 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		TRI56_HUMAN (47-532): 1.21e-51: 195: 17.68
+	Hs
		516745 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		262171 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		TRIM3_HUMAN (122-628): 2.47e-53: 200: 15.85
+	Mm
		857386 TIA1_MOUSE (98-188): 7.57e-10: 62.7: 17.02		TRIM2_MOUSE (109-628): 3.73e-52: 196: 14.63