HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 913
+	Hs
		992763 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		516507 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		516506 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		992762 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1028899 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1028542 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		993710 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1028648 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		516505 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		992760 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		1028897 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		993709 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		1028647 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		992761 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		CUL2_HUMAN (205-913): 0: 746: 27.53
+	Hs
		1028898 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		CUL2_HUMAN (205-913): 0: 746: 27.53
+	Hs
		516503 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		516504 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		CUL2_HUMAN (205-913): 0: 746: 27.53
+	Hs
		1031315 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		1031316 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		CUL2_HUMAN (205-913): 0: 746: 27.53
+	Hs
		516626 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		CUL5_HUMAN (213-913): 0: 610: 26.23