Protein: NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1 (hNAF1)

Gene: NAF1
Organism: Homo sapiens
Interactions: 143
UniProt ID: Q96HR8

Gene Ontology (top 5):
GO:0000454 - snoRNA guided rRNA pseudouridine synthesis
GO:0000493 - box H/ACA snoRNP assembly
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257933

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

8

2

Small-scale

0.972

High

1393393

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

1

High-throughput

0.783

High

1393414

NOP10
H/ACA ribonucleoprotein complex subunit 3

6

1

Small-scale

0.735

High

139583

PESC
Pescadillo homolog

3

1

High-throughput

0.662

High

871999

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

1

High-throughput

0.662

High

1335369

CAMKV
CaM kinase-like vesicle-associated protein

3

1

High-throughput

0.662

High

1393413

E41L5
Band 4.1-like protein 5

3

3

High-throughput

0.662

High

1239646

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

1

High-throughput

0.611

High

1244530

SHQ1
Protein SHQ1 homolog

2

1

Small-scale

0.611

High

1393416

NHP2
H/ACA ribonucleoprotein complex subunit 2

2

1

Small-scale

0.611

High

1357690

SNX33
Sorting nexin-33

3

1

High-throughput

0.607

High

250314

VINEX
Vinexin

2

1

High-throughput

0.606

High

911341

IMA5
Importin subunit alpha-5

2

1

High-throughput

0.601

High

274044

CREST
Calcium-responsive transactivator

2

0

High-throughput

0.580

High

772188

MSX2
Homeobox protein MSX-2

2

0

High-throughput

0.580

High

1061822

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

1124392

ELOA1
Elongin-A

2

0

High-throughput

0.580

High

1332299

BOLL
Protein boule-like

2

0

High-throughput

0.580

High

1381891

TET5B
Terminal nucleotidyltransferase 5B

2

0

High-throughput

0.580

High

1393400

RAMAC
RNA guanine-N7 methyltransferase activating subunit

2

0

High-throughput

0.580

High

1393426

MED31
Mediator of RNA polymerase II transcription subunit 31

2

0

High-throughput

0.580

High

1393428

MAGD1
Melanoma-associated antigen D1

2

0

High-throughput

0.580

High

1393424

E41L3
Band 4.1-like protein 3

2

3

High-throughput

0.574

High

286402

DAB1
Disabled homolog 1

1

1

High-throughput

0.573

High

1331837

SYT2
Synaptotagmin-2

2

1

High-throughput

0.549

High

1393408

E41L1
Band 4.1-like protein 1

2

3

High-throughput

0.549

High

211388

RFOX2
RNA binding protein fox-1 homolog 2

1

0

High-throughput

0.549

High

253677

IMA7
Importin subunit alpha-7

1

1

High-throughput

0.536

High

269803

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

1

High-throughput

0.536

High

477838

RM03
Large ribosomal subunit protein uL3m

1

1

High-throughput

0.536

High

986862

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

1

High-throughput

0.536

High

1032392

OTUD4
OTU domain-containing protein 4

1

1

High-throughput

0.536

High

1120035

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

1

High-throughput

0.536

High

1347138

WDR48
WD repeat-containing protein 48

1

1

High-throughput

0.536

High

1351857

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.536

High

1393402

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.536

High

1393429

SNX9
Sorting nexin-9

1

1

High-throughput

0.536

High

997940

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.527

High

518894

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.513

High

628831

TBP
TATA-box-binding protein

1

0

High-throughput

0.513

High

839341

MTOR
Serine/threonine-protein kinase mTOR

1

0

High-throughput

0.513

High

849224

KSYK
Tyrosine-protein kinase SYK

1

0

High-throughput

0.513

High

935945

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.513

High

1055954

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.513

High

1100634

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.513

High

1121494

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.513

High

1149813

TAF13
Transcription initiation factor TFIID subunit 13

1

0

High-throughput

0.513

High

1150308

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.513

High

1150341

TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A

1

0

High-throughput

0.513

High

1191606

RABL6
Rab-like protein 6

1

0

High-throughput

0.513

High

1200513

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

1

0

High-throughput

0.513

High

1228208

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

0

High-throughput

0.513

High

1325072

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

1368354

REQU
Zinc finger protein ubi-d4

1

0

High-throughput

0.513

High

1383729

MIB2
E3 ubiquitin-protein ligase MIB2

1

0

High-throughput

0.513

High

1384405

PF21A
PHD finger protein 21A

1

0

High-throughput

0.513

High

1391702

AURKB
Aurora kinase B

1

0

High-throughput

0.513

High

1393396

RANB9
Ran-binding protein 9

1

0

High-throughput

0.513

High

1393409

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

High-throughput

0.513

High

1393417

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

0

High-throughput

0.513

High

1393421

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

1393430

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

1139111

DAZP2
DAZ-associated protein 2

1

0

High-throughput

0.493

High

1382817

FUBP1
Far upstream element-binding protein 1

1

0

High-throughput

0.493

High

993711

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.481

High

971876

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.480

High

286030

SF3B1
Splicing factor 3B subunit 1

1

1

High-throughput

0.479

High

643981

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

Small-scale

0.479

High

693907

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

703024

DPOD1
DNA polymerase delta catalytic subunit

1

1

High-throughput

0.479

High

1138511

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1163751

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

3

High-throughput

0.479

High

1215770

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1347836

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.479

High

1393398

E2AK1
Eukaryotic translation initiation factor 2-alpha kinase 1

1

2

High-throughput

0.479

High

1393410

BRD9
Bromodomain-containing protein 9

1

1

High-throughput

0.479

High

1393411

SP110
Sp110 nuclear body protein

1

1

High-throughput

0.479

High

1393412

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

1393415

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

1393420

DDX20
Probable ATP-dependent RNA helicase DDX20

1

1

High-throughput

0.479

High

1270720

Q7KZS0
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.470

High

173227

XPO1
Exportin-1

1

0

High-throughput

0.458

High

279459

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

401299

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

472981

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

607002

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

762034

GRK5
G protein-coupled receptor kinase 5

1

0

High-throughput

0.458

High

770258

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

831242

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

855494

ATRX
Transcriptional regulator ATRX

1

0

High-throughput

0.458

High

935599

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.458

High

1045641

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1212081

SPOUT
28S rRNA

1

0

Small-scale

0.458

High

1289535

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1393394

EAF1
ELL-associated factor 1

1

0

High-throughput

0.458

High

1393395

RBM14
RNA-binding protein 14

1

0

High-throughput

0.458

High

1393403

TRI31
E3 ubiquitin-protein ligase TRIM31

1

0

High-throughput

0.458

High

1393404

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1393418

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.458

High

1393419

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1393422

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

74737

B2WTI3
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

1

High-throughput

0.445

High

639159

SYT1
Synaptotagmin-1

1

1

High-throughput

0.445

High

767301

MERL
Merlin

1

3

High-throughput

0.445

High

1393397

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

1

High-throughput

0.445

High

1280038

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

1

High-throughput

0.439

High

1227253

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

216017

FIBP
Acidic fibroblast growth factor intracellular-binding protein

1

0

High-throughput

0.426

High

722882

SSR2
Somatostatin receptor type 2

1

0

High-throughput

0.426

High

1054135

BTK
Tyrosine-protein kinase BTK

1

0

High-throughput

0.426

High

1209514

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1334354

IN80E
INO80 complex subunit E

1

0

High-throughput

0.426

High

1393401

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.426

High

1393425

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.426

High

107407

F8W7C6
Ribosomal protein L10

1

2

High-throughput

0.407

High

107439

F8WC19
Splicing factor 3b subunit 1

1

1

High-throughput

0.407

High

1369294

EDA
Ectodysplasin-A

4

0

High-throughput

0.360

High

1364813

F168A
Protein FAM168A

3

0

High-throughput

0.352

High

1317039

FAM9A
Protein FAM9A

3

0

High-throughput

0.347

High

441446

CHLE
Cholinesterase

2

0

High-throughput

0.328

High

640612

MK
Midkine

2

0

High-throughput

0.328

High

1393407

SMOC1
SPARC-related modular calcium-binding protein 1

2

0

High-throughput

0.328

High

1186591

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.316

High

1186683

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

1187905

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.316

High

1278895

KR193
Keratin-associated protein 19-3

2

0

High-throughput

0.316

High

1393399

HERP2
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

2

0

High-throughput

0.316

High

1393406

NUAK2
NUAK family SNF1-like kinase 2

2

0

High-throughput

0.313

High

50830

CA226
Uncharacterized protein C1orf226

1

0

High-throughput

0.279

Low

829495

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

939820

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

0

High-throughput

0.279

Low

1023969

EM55
55 kDa erythrocyte membrane protein

1

0

High-throughput

0.279

Low

1311014

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

1346613

VANG1
Vang-like protein 1

1

0

High-throughput

0.279

Low

1359738

HPSE2
Inactive heparanase-2

1

0

High-throughput

0.279

Low

1393405

CHST5
Carbohydrate sulfotransferase 5

1

0

High-throughput

0.279

Low

1393423

ICAM5
Intercellular adhesion molecule 5

1

0

High-throughput

0.279

Low

106460

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

126166

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.249

Low

516118

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low

914468

EFNB2
Ephrin-B2

1

0

High-throughput

0.232

Low

1393427

INSL6
Insulin-like peptide INSL6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025