HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: RBM23 (Q86U06)
Probable RNA-binding protein 23 (CAPER beta) (CAPERbeta) (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2)
Gene: RBM23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0006397 - mRNA processing GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 439
+	Hs
		1028979 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		RBM23_HUMAN (1-439): 2.05e-97: 300: 100.00
+	Hs
		992769 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		RBM39_HUMAN (7-438): 3.43e-71: 235: 54.40
+	Hs
		1028909 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		RBM39_HUMAN (7-438): 3.43e-71: 235: 54.40
+	Hs
		1028546 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		RBM39_HUMAN (7-438): 3.43e-71: 235: 54.40
+	Hs
		993716 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		RBM39_HUMAN (7-438): 3.43e-71: 235: 54.40
+	Mm
		857340 SRSF1_MOUSE (3-166): 2.36e-57: 192: 41.42		TIA1_MOUSE (63-438): 8.6e-64: 212: 16.54
+	Mm
		857324 Q542V3_MOUSE (1-468): 2.02e-54: 191: 80.38		TIA1_MOUSE (63-438): 8.6e-64: 212: 16.54
+	Hs
		992984 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		PUF60_HUMAN (146-439): 2.95e-59: 204: 21.12
+	Hs
		516518 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		RBM39_HUMAN (7-438): 3.43e-71: 235: 54.40
+	Mm
		665745 PABP1_MOUSE (1-189): 6.69e-31: 128: 19.50		TIA1_MOUSE (63-438): 8.6e-64: 212: 16.54
+	Hs
		474020 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		PAB4L_HUMAN (167-354): 1.25e-42: 155: 27.51
+	Hs
		516730 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PUF60_HUMAN (146-439): 2.95e-59: 204: 21.12
+	Sc
		376750 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		PABP_YEAST (52-250): 1.14e-21: 99.6: 12.68
+	Hs
		1028926 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		SF3B4_HUMAN (251-359): 7.73e-23: 101: 32.14
+	Hs
		516478 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		PABP1_HUMAN (253-349): 2.65e-17: 86.5: 31.96
+	Hs
		516493 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		PABP1_HUMAN (253-349): 2.65e-17: 86.5: 31.96
+	Hs
		516495 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PABP4_HUMAN (23-265): 1.46e-28: 120: 13.66
+	Cn
		111495 J9VJ75_CRYNH (3-179): 9.05e-43: 161: 30.85		J9VUR9_CRYNH (262-351): 5.3e-14: 76.1: 30.00
+	Hs
		516339 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PABP1_HUMAN (253-349): 2.65e-17: 86.5: 31.96
+	Hs
		516689 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PABP3_HUMAN (253-349): 7.05e-16: 81.8: 28.87