HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: CCNL2 (Q96S94)
Cyclin-L2 (Paneth cell-enhanced expression protein)
Gene: CCNL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	18216018
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 520
+	Hs
		992895 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		CCNL2_HUMAN (33-520): 1.65e-99: 311: 100.00
+	Hs
		1029048 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		CCNL2_HUMAN (33-520): 1.65e-99: 311: 100.00
+	Hs
		1028780 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		CCNL2_HUMAN (33-520): 1.65e-99: 311: 100.00
+	Hs
		992986 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	Hs
		1029152 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	Mm
		1161052 SRSF1_MOUSE (3-166): 2.36e-57: 192: 41.42		CCNT1_MOUSE (44-496): 1.42e-75: 254: 18.83
+	Hs
		993865 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	Hs
		1028867 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	At
		1325350 PABP8_ARATH (68-185): 1.6e-11: 68.9: 19.51		CCB24_ARATH (23-316): 1.77e-77: 251: 14.53
+	At
		186467 PABP4_ARATH (1-183): 6.73e-30: 125: 17.95		CCH11_ARATH (64-353): 4.99e-53: 184: 16.89
+	Sc
		376841 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		SSN8_YEAST (60-297): 1.58e-61: 206: 20.60
+	Sc
		633960 GBP2_YEAST (4-201): 2.69e-25: 109: 20.19		CTK2_YEAST (84-284): 1.3e-23: 103: 20.20