HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31300519
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 581
+	Hs
		516675 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1031446 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		681823 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		682172 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		AKT2_HUMAN (115-573): 1.5e-117: 358: 12.66
+	Rn
		1144336 PABP1_RAT (1-189): 4.87e-31: 128: 19.50		AKT3_RAT (110-552): 1.87e-118: 361: 14.16
+	Hs
		1028664 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Hs
		516351 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		568649 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Sc
		742049 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		BCK1_YEAST (254-528): 1.14e-45: 175: 23.51
+	Hs
		963583 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62