HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: DDX24 (Q9GZR7)
ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)
Gene: DDX24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 859
+	Hs
		992921 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		1029084 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		1028811 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		1308762 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		133858 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Mm
		936480 TIAR_MOUSE (3-105): 3.23e-13: 73.1: 19.05		DDX5_MOUSE (232-774): 8.32e-123: 385: 19.89
+	Hs
		134018 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Sc
		376580 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		DED1_YEAST (255-734): 7.5e-120: 377: 23.74
+	Sc
		742005 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		MAK5_YEAST (385-811): 2.71e-65: 235: 33.13
+	Sc
		699671 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		DRS1_YEAST (391-692): 3.86e-37: 151: 35.51
+	Sc
		742058 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		HAS1_YEAST (391-743): 2.77e-35: 142: 30.25
+	Hs
		992985 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1029127 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		1029151 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1028630 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1028843 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		993864 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1028866 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Sc
		376755 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		MAK5_YEAST (385-811): 2.71e-65: 235: 33.13
+	Mm
		1208005 RBM4_MOUSE (1-218): 3.79e-19: 90.8: 23.85		DDX18_MOUSE (381-740): 8.81e-32: 134: 29.43