HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 783
+	Hs
		1029122 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1028626 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1028839 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		516711 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1344201 S4R3G0_HUMAN (3-109): 1.87e-26: 105: 36.61		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		992907 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1029059 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1028788 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Mm
		936482 TIAR_MOUSE (3-105): 3.23e-13: 73.1: 19.05		Q8K2L4_MOUSE (101-783): 2.92e-167: 501: 86.17
+	Hs
		133858 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Mm
		936480 TIAR_MOUSE (3-105): 3.23e-13: 73.1: 19.05		DDX5_MOUSE (92-620): 1.44e-136: 419: 24.81
+	Hs
		1308743 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		134018 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		757583 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757595 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757593 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757584 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757594 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		516391 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Sc
		376580 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		DED1_YEAST (196-541): 2.98e-56: 205: 37.98