HitPredict

Interactor 1: DHX9 (Q08211)
ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A)
Gene: DHX9

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.689

The method score is based on:

Property Details
Experiments 26902284, 17932509, 17531811, 19955415
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000993 - RNA polymerase II complex binding
GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
GO:0003727 - single-stranded RNA binding
GO:0005634 - nucleus
and 12 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1270
Hs

1 859
+ Hs
+ Mm
+ Dr
+ Mm
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+ Hs
+ Hs
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+ Mm
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+ Dr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024