HitPredict

Interactor 1: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Interactor 2: RRS1 (Q08746)
Regulator of ribosome biosynthesis
Gene: RRS1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	37968396, 22319211
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Brix~RRS1
Common GO terms	GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 291 Sc			1 203
+	Hs
		1065839 BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91		RRS1_HUMAN (4-202): 4.34e-62: 198: 37.69
+	Sc
		733965 RPF2_YEAST (6-282): 1.45e-61: 199: 16.84		RRS1_YEAST (1-203): 4.11e-80: 239: 100.00
+	Hs
		1065883 RPF2_HUMAN (1-285): 3.52e-77: 238: 17.57		RRS1_HUMAN (4-202): 4.34e-62: 198: 37.69
+	Sc
		755346 RPF1_YEAST (4-252): 5.84e-52: 173: 14.40		RRS1_YEAST (1-203): 4.11e-80: 239: 100.00
+	Sc
		754929 SSF1_YEAST (10-197): 9.05e-34: 129: 15.64		RRS1_YEAST (1-203): 4.11e-80: 239: 100.00
+	Sp
		223477 RPF2_SCHPO (4-280): 1.39e-59: 194: 13.47		RRS1_SCHPO (9-191): 6.95e-53: 168: 45.90