HitPredict

Interactor 1: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Interactor 2: YTM1 (Q12024)
Ribosome biogenesis protein YTM1 (Microtubule-associated protein YTM1)
Gene: YTM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	16287855, 16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 291 Sc			1 460
+	Sc
		733969 RPF2_YEAST (6-282): 1.45e-61: 199: 16.84		YTM1_YEAST (1-460): 5.89e-107: 326: 100.00
+	Sc
		755348 RPF1_YEAST (4-252): 5.84e-52: 173: 14.40		YTM1_YEAST (1-460): 5.89e-107: 326: 100.00
+	Sc
		754933 SSF1_YEAST (10-197): 9.05e-34: 129: 15.64		YTM1_YEAST (1-460): 5.89e-107: 326: 100.00
+	Sc
		1014869 SSF2_YEAST (10-197): 8.32e-33: 127: 15.17		YTM1_YEAST (1-460): 5.89e-107: 326: 100.00
+	Hs
		1255224 BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91		NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24
+	Hs
		1332921 RPF2_HUMAN (1-285): 3.52e-77: 238: 17.57		NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24
+	Sc
		630856 RPF2_YEAST (6-282): 1.45e-61: 199: 16.84		NLE1_YEAST (19-130): 2.91e-11: 67.5: 15.28
+	Sc
		630859 SSF1_YEAST (10-197): 9.05e-34: 129: 15.64		NLE1_YEAST (19-130): 2.91e-11: 67.5: 15.28