HitPredict

Interactor 1: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Interactor 2: DBP10 (Q12389)
ATP-dependent RNA helicase DBP10 (EC 3.6.4.13) (DEAD box protein 10)
Gene: DBP10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	16429126, 37968396, 38113283
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 291 Sc			1 995
+	Sc
		733986 RPF2_YEAST (6-282): 1.45e-61: 199: 16.84		DBP10_YEAST (1-995): 0: 592: 100.00
+	Sc
		755353 RPF1_YEAST (4-252): 5.84e-52: 173: 14.40		DBP10_YEAST (1-995): 0: 592: 100.00
+	Sc
		754940 SSF1_YEAST (10-197): 9.05e-34: 129: 15.64		DBP10_YEAST (1-995): 0: 592: 100.00
+	Sc
		624185 BRX1_YEAST (1-291): 1.12e-99: 295: 100.00		DBP2_YEAST (32-566): 6.82e-130: 405: 22.20
+	Hs
		1254818 SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87		DDX54_HUMAN (59-993): 3.77e-127: 409: 29.88
+	Sc
		415968 SSF1_YEAST (10-197): 9.05e-34: 129: 15.64		DED1_YEAST (66-567): 3.3e-128: 403: 25.24
+	Hs
		1292660 SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87		DDX27_HUMAN (138-547): 1.72e-51: 196: 33.66