Interactor 1: MED7 (Q08278)
Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7)
Gene: MED7

Interactor 2: MED4 (Q12343)
Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4)
Gene: MED4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 10688190, 11805826, 11555651, 9420330, 9892641, 15710619, 15477388, 16554755, 16429126, 16962561, 26317468, 28575439, 33933450, 37968396, 20123732, 14759368
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, biochemical, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Med4~Med7
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 222
Sc

1 284
+ Ca

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024