HitPredict

Interactor 1: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Interactor 2: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 17721511, 22057045
Identification Methods protein kinase assay, anti bait coimmunoprecipitation
Interaction Type phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains F5_F8_type_C~F5_F8_type_C, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0001558 - regulation of cell growth
GO:0001952 - regulation of cell-matrix adhesion
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005518 - collagen binding
GO:0005524 - ATP binding
and 24 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

1 913
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Last updated: 15 Jul 2024