HitPredict

Interactor 1: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Interactor 2: TSN17 (Q96FV3)
Tetraspanin-17 (Tspan-17) (F-box only protein 23) (Tetraspan protein SB134) (Transmembrane 4 superfamily member 17)
Gene: TSPAN17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 913 Hs			1 270
+	Hs
		994655 DDR1_HUMAN (1-913): 0: 911: 100.00		TSN33_HUMAN (2-266): 2.82e-76: 235: 44.15
+	Hs
		326059 DDR1_HUMAN (1-913): 0: 911: 100.00		TSN15_HUMAN (16-264): 2.04e-61: 197: 32.93
+	Hs
		446002 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		CD63_HUMAN (12-265): 6.93e-56: 181: 27.95
+	Rn
		659441 SRC_RAT (361-912): 4.24e-126: 393: 23.42		CD63_RAT (12-265): 2.14e-54: 177: 27.56
+	Hs
		237780 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		TSN3_HUMAN (13-262): 1.18e-43: 150: 21.03
+	Hs
		237786 FGFR2_HUMAN (583-905): 4.2e-109: 357: 34.05		TSN3_HUMAN (13-262): 1.18e-43: 150: 21.03
+	Hs
		237779 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		TSN3_HUMAN (13-262): 1.18e-43: 150: 21.03
+	Hs
		237717 FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16		TSN2_HUMAN (16-157): 5.01e-13: 68.6: 34.25