HitPredict

Interactor 1: GATA4 (Q08369)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Interactor 2: MED1 (Q925J9)
Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2)
Gene: MED1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

The method score is based on:

Property	Details
Experiments	20211142
Identification Methods	two hybrid
Interaction Type	direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001223 - transcription coactivator binding GO:0001701 - in utero embryonic development and 12 others more... GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0007507 - heart development GO:0010628 - positive regulation of gene expression GO:0035050 - embryonic heart tube development GO:0043066 - negative regulation of apoptotic process GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	441
Mm

1	1575

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024