HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005925 - focal adhesion GO:0007015 - actin filament organization GO:0015629 - actin cytoskeleton GO:0030017 - sarcomere GO:0030027 - lamellipodium
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 474
+	Hs
		953179 ACTB_HUMAN (4-377): 0: 598: 94.12		COR1C_HUMAN (1-474): 1.23e-137: 406: 100.00
+	Hs
		993381 ACTG_HUMAN (4-377): 0: 598: 94.39		COR1C_HUMAN (1-474): 1.23e-137: 406: 100.00
+	Hs
		995794 ACTC_HUMAN (1-377): 0: 599: 100.00		COR1B_HUMAN (2-472): 5.26e-123: 369: 71.73
+	Hs
		995756 ACTC_HUMAN (1-377): 0: 599: 100.00		SNR40_HUMAN (2-200): 4.35e-40: 149: 18.72
+	Hs
		953006 ACTB_HUMAN (4-377): 0: 598: 94.12		COR2A_HUMAN (4-212): 4.19e-25: 110: 10.46
+	Hs
		993279 ACTG_HUMAN (4-377): 0: 598: 94.39		COR2A_HUMAN (4-212): 4.19e-25: 110: 10.46
+	Hs
		945132 ACTB_HUMAN (4-377): 0: 598: 94.12		CORO7_HUMAN (3-203): 6.99e-23: 104: 12.73
+	Hs
		952708 ACTB_HUMAN (4-377): 0: 598: 94.12		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		964830 ACTG_HUMAN (4-377): 0: 598: 94.39		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		995621 ACTC_HUMAN (1-377): 0: 599: 100.00		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08