HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0045202 - synapse GO:0051893 - regulation of focal adhesion assembly
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 474
+	Hs
		953179 ACTB_HUMAN (1-375): 0: 604: 98.93		COR1C_HUMAN (1-474): 1.23e-137: 406: 100.00
+	Hs
		995892 ACTC_HUMAN (2-375): 0: 594: 94.39		COR1C_HUMAN (1-474): 1.23e-137: 406: 100.00
+	Hs
		995794 ACTC_HUMAN (2-375): 0: 594: 94.39		COR1B_HUMAN (2-472): 5.26e-123: 369: 71.73
+	Hs
		965001 ACTBL_HUMAN (2-375): 0: 734: 91.44		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		965037 POTEE_HUMAN (1-375): 0: 729: 91.47		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		995756 ACTC_HUMAN (2-375): 0: 594: 94.39		SNR40_HUMAN (2-200): 4.35e-40: 149: 18.72
+	Hs
		953006 ACTB_HUMAN (1-375): 0: 604: 98.93		COR2A_HUMAN (4-212): 4.19e-25: 110: 10.46
+	Hs
		993279 ACTG_HUMAN (1-375): 0: 604: 100.00		COR2A_HUMAN (4-212): 4.19e-25: 110: 10.46
+	Hs
		945132 ACTB_HUMAN (1-375): 0: 604: 98.93		CORO7_HUMAN (3-203): 6.99e-23: 104: 12.73
+	Hs
		952708 ACTB_HUMAN (1-375): 0: 604: 98.93		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		964830 ACTG_HUMAN (1-375): 0: 604: 100.00		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Sc
		948664 ACT_YEAST (1-375): 0: 592: 89.07		CORO_YEAST (2-164): 4.85e-15: 79.6: 12.64
+	Hs
		995621 ACTC_HUMAN (2-375): 0: 594: 94.39		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08