HitPredict

Interactor 1: DSC1 (Q08554)
Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3)
Gene: DSC1

Interactor 2: FND3A (Q9Y2H6)
Fibronectin type-III domain-containing protein 3A (Human gene expressed in odontoblasts)
Gene: FNDC3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32963011
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0098609 - cell-cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 1198
+	Rn
		1145482 CADH2_RAT (21-890): 0: 728: 31.35		PTPRF_RAT (27-1187): 2.18e-160: 526: 15.25
+	Hs
		1032047 PCDG7_HUMAN (3-842): 0: 821: 18.46		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		617032 PCDGG_HUMAN (1-842): 0: 788: 18.08		PTPRD_HUMAN (657-1184): 9.09e-61: 231: 13.37
+	Hs
		1377234 PCDG5_HUMAN (2-346): 3.54e-55: 208: 18.18		FND3A_HUMAN (1-1198): 0: 783: 100.00
+	Hs
		489891 CADH1_HUMAN (23-890): 0: 699: 29.13		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		521907 CADH1_HUMAN (23-890): 0: 699: 29.13		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Mm
		472760 CADH2_MOUSE (23-890): 0: 727: 31.20		PTPRQ_MOUSE (69-924): 3.95e-65: 245: 15.95
+	Hs
		521727 CADH1_HUMAN (23-890): 0: 699: 29.13		PTPRD_HUMAN (657-1184): 9.09e-61: 231: 13.37
+	Mm
		454937 CADH1_MOUSE (7-890): 0: 670: 29.11		PTPRQ_MOUSE (69-924): 3.95e-65: 245: 15.95
+	Hs
		522100 CADH1_HUMAN (23-890): 0: 699: 29.13		TITIN_HUMAN (12-282): 4.47e-09: 63.5: 8.99
+	Hs
		490044 PCDGD_HUMAN (1-464): 1.17e-84: 293: 16.98		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		1032046 PCDGD_HUMAN (1-464): 1.17e-84: 293: 16.98		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		1123263 PCDGD_HUMAN (1-464): 1.17e-84: 293: 16.98		SDK2_HUMAN (29-947): 1.19e-70: 262: 15.15
+	Hs
		1018316 PCDGD_HUMAN (1-464): 1.17e-84: 293: 16.98		CNTN1_HUMAN (10-843): 6.75e-71: 259: 14.44
+	Hs
		490028 PCDBG_HUMAN (2-369): 1.91e-53: 201: 17.49		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Mm
		472766 DSG1A_MOUSE (128-567): 8.15e-61: 226: 32.13		PTPRQ_MOUSE (69-924): 3.95e-65: 245: 15.95
+	Hs
		617023 PCDBG_HUMAN (2-369): 1.91e-53: 201: 17.49		PTPRD_HUMAN (657-1184): 9.09e-61: 231: 13.37
+	Hs
		617033 PCDB6_HUMAN (2-346): 3.11e-50: 192: 17.08		PTPRD_HUMAN (657-1184): 9.09e-61: 231: 13.37
+	Hs
		617035 PCDG6_HUMAN (477-884): 1.97e-27: 121: 12.56		PTPRD_HUMAN (657-1184): 9.09e-61: 231: 13.37
+	Hs
		616974 DSC3_HUMAN (1-331): 4.44e-27: 120: 12.75		PTPRD_HUMAN (657-1184): 9.09e-61: 231: 13.37