Interactor 1: RPN8 (Q08723)
26S proteasome regulatory subunit RPN8
Gene: RPN8
Interactor 2: RPN6 (Q12377)
26S proteasome regulatory subunit RPN6 (Proteasome non-ATPase subunit 4)
Gene: RPN6
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.974 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11805826, 14759368, 23911091, 24412063, 15102831, 9741626, 16554755, 16429126, 18467557, 37968396 |
| Identification Methods | tandem affinity purification, affinity chromatography technology, biochemical, protein complementation assay, dihydrofolate reductase reconstruction, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | JAB~PCI, MitMem_reg~PCI, MitMem_reg~RPN6_C_helix |
| Common GO terms | GO:0000502 - proteasome complex GO:0006511 - ubiquitin-dependent protein catabolic process GO:0008541 - proteasome regulatory particle, lid subcomplex GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
