Interactor 1: RUNX2 (Q08775)
Runt-related transcription factor 2 (Acute myeloid leukemia 3 protein) (Core-binding factor subunit alpha-1) (CBF-alpha-1) (Oncogene AML-3) (Osteoblast-specific transcription factor 2) (OSF-2) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEA2-alpha A) (PEBP2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit)
Gene: RUNX2

Interactor 2: HDAC4 (Q6NZM9)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 15537544
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001501 - skeletal system development
GO:0001649 - osteoblast differentiation
GO:0002076 - osteoblast development
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 9 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 607
Mm

1 1076
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024