HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30110629, 33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 2414
+	Hs
		881798 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		818793 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		996921 SSRP1_HUMAN (1-709): 0: 805: 100.00		BRWD1_HUMAN (1007-1168): 2.52e-44: 180: 32.93
+	Hs
		996961 SSRP1_HUMAN (1-709): 0: 805: 100.00		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		631411 SSRP1_HUMAN (1-709): 0: 805: 100.00		BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20
+	Hs
		996682 SSRP1_HUMAN (1-709): 0: 805: 100.00		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		996791 SSRP1_HUMAN (1-709): 0: 805: 100.00		PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86
+	Hs
		996741 SSRP1_HUMAN (1-709): 0: 805: 100.00		PB1_HUMAN (1081-1145): 9.68e-11: 69.8: 36.92
+	Hs
		996721 SSRP1_HUMAN (1-709): 0: 805: 100.00		BRWD3_HUMAN (1006-1157): 1.89e-10: 68.9: 27.93
+	Sc
		979855 POB3_YEAST (4-504): 0: 541: 29.66		BDF2_YEAST (1072-1149): 1.81e-11: 71.6: 44.87
+	Sc
		728756 POB3_YEAST (4-504): 0: 541: 29.66		BDF1_YEAST (1041-1152): 6.84e-09: 63.2: 37.61
+	Hs
		1300957 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31
+	Hs
		881838 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		1067153 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		1300971 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02
+	Hs
		1270803 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Hs
		881831 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02
+	Hs
		881814 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		PB1_HUMAN (1081-1145): 9.68e-11: 69.8: 36.92
+	Hs
		818819 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13
+	Hs
		818817 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		PB1_HUMAN (1081-1145): 9.68e-11: 69.8: 36.92